2-(Pyridinyl)-4,5,6-pyrimidinetriamines

Details 2-(Pyridinyl)-4,5,6-pyrimidinetriamines 2-(Pyridinyl)-4,5,6-pyrimidinetriamines

1984-05-21

1985-03-05

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C07D40104

Patent

active

045032289

ABSTRACT:
8-Q-2-PY-9H-purin-6-amines (II), salts thereof, their preparation via 2-PY-4,5,6-pyrimidinetriamine and cardiotonic use are shown, where PY is 4-pyridinyl or 4-pyridinyl having one or two lower-alkyl substituents, and Q is methyl, ethyl, 1-methylethyl, 1,1-dimethylethyl, methylthio and ethylthio. Also shown as intermediates for the compounds where Q is methylthio or ethylthio are the corresponding 6-amino-2-PY-9H-purin-8-thiols.

REFERENCES:
patent: 3041340 (1962-06-01), Bullock et al.
Taylor et al., [J. Am. Chem. Soc. 81, 2442-2448 (1959)].
Baddiley et al., [J. Chem. Soc. 1943, pp. 386-387].

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