Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2007-03-26
2010-06-15
Berch, Mark L (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C514S263400, C544S244000, C544S277000, C544S386000, C544S389000, C544S403000, C544S295000, C544S404000, C536S027600, C536S027620, C536S027300, C546S226000, C546S227000, C568S807000, C568S828000, C558S260000
Reexamination Certificate
active
07737127
ABSTRACT:
The invention provides compounds having the following general formula (I):wherein X, R1, R2, R7and Z are as described here.
REFERENCES:
patent: 3892777 (1975-07-01), Gruenman et al.
patent: 4012495 (1977-03-01), Schmiechen et al.
patent: 4193926 (1980-03-01), Schmiechen et al.
patent: 4242345 (1980-12-01), Brenner et al.
patent: 4559157 (1985-12-01), Smith et al.
patent: 4608392 (1986-08-01), Jacquet et al.
patent: 4665074 (1987-05-01), Amschler
patent: 4820508 (1989-04-01), Wortzman
patent: 4824660 (1989-04-01), Angello et al.
patent: 4879296 (1989-11-01), Daluge et al.
patent: 4938949 (1990-07-01), Borch et al.
patent: 4956345 (1990-09-01), Miyasaka et al.
patent: 4965271 (1990-10-01), Mandell et al.
patent: 4968697 (1990-11-01), Hutchison
patent: 4992478 (1991-02-01), Geria
patent: 5070877 (1991-12-01), Mohiuddin et al.
patent: 5096906 (1992-03-01), Mandell et al.
patent: 5124455 (1992-06-01), Lombardo et al.
patent: 5140015 (1992-08-01), Olsson et al.
patent: 5189027 (1993-02-01), Miyashita et al.
patent: 5272153 (1993-12-01), Mandell et al.
patent: 5278150 (1994-01-01), Olsson et al.
patent: 5298508 (1994-03-01), Jacobson et al.
patent: 5364862 (1994-11-01), Spada et al.
patent: 5561134 (1996-10-01), Spada et al.
patent: 5565462 (1996-10-01), Eitan et al.
patent: 5593973 (1997-01-01), Carter
patent: 5593975 (1997-01-01), Cristalli
patent: 5593976 (1997-01-01), Mongelli et al.
patent: 5665754 (1997-09-01), Feldman et al.
patent: 5668139 (1997-09-01), Belardinelli et al.
patent: 5696254 (1997-12-01), Mansour et al.
patent: 5731296 (1998-03-01), Sollevi
patent: 5756706 (1998-05-01), Mansour et al.
patent: 5776940 (1998-07-01), Daluge et al.
patent: 5854081 (1998-12-01), Linden et al.
patent: 5877180 (1999-03-01), Linden et al.
patent: 5932558 (1999-08-01), Cronstein et al.
patent: 5998386 (1999-12-01), Feldman
patent: 6004945 (1999-12-01), Fukunaga
patent: RE36494 (2000-01-01), Olsson et al.
patent: 6020321 (2000-02-01), Cronstein et al.
patent: 6020339 (2000-02-01), Perrier et al.
patent: 6034089 (2000-03-01), Han et al.
patent: 6060481 (2000-05-01), LaNoue et al.
patent: 6117878 (2000-09-01), Linden et al.
patent: 6232297 (2001-05-01), Linden et al.
patent: 6303619 (2001-10-01), Linden et al.
patent: 6322771 (2001-11-01), Linden et al.
patent: 6326359 (2001-12-01), Monaghan et al.
patent: 6332771 (2001-12-01), Adams et al.
patent: 6339072 (2002-01-01), Martin et al.
patent: 6350735 (2002-02-01), Monaghan
patent: 6387889 (2002-05-01), Endo et al.
patent: 6407076 (2002-06-01), Box et al.
patent: 6448235 (2002-09-01), Linden et al.
patent: 6514949 (2003-02-01), Linden et al.
patent: 6525032 (2003-02-01), Mantrell et al.
patent: 6531457 (2003-03-01), Linden et al.
patent: 6545002 (2003-04-01), Linden et al.
patent: 6624158 (2003-09-01), Mantell et al.
patent: 6670334 (2003-12-01), Linden
patent: 6936596 (2005-08-01), Konno et al.
patent: 7214665 (2007-05-01), Linden et al.
patent: 7226913 (2007-06-01), Linden et al.
patent: 7307079 (2007-12-01), Den Hartog et al.
patent: 7378400 (2008-05-01), Rieger et al.
patent: 7396825 (2008-07-01), Okusa et al.
patent: 7427606 (2008-09-01), Linden et al.
patent: 7442687 (2008-10-01), Rieger et al.
patent: 7576069 (2009-08-01), Rieger et al.
patent: 7605143 (2009-10-01), Rieger et al.
patent: 2001/0027185 (2001-10-01), Linden et al.
patent: 2002/0032168 (2002-03-01), Mantrell et al.
patent: 2002/0058641 (2002-05-01), Mantell et al.
patent: 2002/0072597 (2002-06-01), Mantell et al.
patent: 2003/0013675 (2003-01-01), Yeadon et al.
patent: 2003/0162742 (2003-08-01), Linden et al.
patent: 2003/0186926 (2003-10-01), Linden et al.
patent: 2005/0182018 (2005-08-01), Linden et al.
patent: 2005/0261236 (2005-11-01), Okusa et al.
patent: 2005/0282831 (2005-12-01), Beauglehole et al.
patent: 2006/0040888 (2006-02-01), Rieger et al.
patent: 2006/0040889 (2006-02-01), Rieger et al.
patent: 2006/0100169 (2006-05-01), Rieger et al.
patent: 2006/0128652 (2006-06-01), Jagtap et al.
patent: 2006/0217343 (2006-09-01), Rieger et al.
patent: 2007/0265440 (2007-11-01), Linden et al.
patent: 2008/0009460 (2008-01-01), Linden et al.
patent: 2008/0027022 (2008-01-01), Linden et al.
patent: 2008/0064653 (2008-03-01), Li et al.
patent: 2008/0262001 (2008-10-01), Kranenburg et al.
patent: 2008/0312160 (2008-12-01), Guerrant et al.
patent: 2009/0118309 (2009-05-01), Beauglehole et al.
patent: 2009/0162282 (2009-06-01), Thompson et al.
patent: 2009/0162292 (2009-06-01), Thompson et al.
patent: 2009/0170803 (2009-07-01), Linden et al.
patent: 2009/0253647 (2009-10-01), Rieger et al.
patent: 2009/0280059 (2009-11-01), Rieger et al.
patent: 2009/0298788 (2009-12-01), Rieger et al.
patent: 0488331 (1992-06-01), None
patent: 0488336 (1992-06-01), None
patent: 0488336 (1995-05-01), None
patent: 488336 (1995-05-01), None
patent: 0700908 (1996-03-01), None
patent: 1194440 (2002-04-01), None
patent: 1150991 (2004-04-01), None
patent: 174074 (1979-10-01), None
patent: 05163294 (1993-06-01), None
patent: 07508718 (1995-09-01), None
patent: 530976 (2005-07-01), None
patent: WO-93/22328 (1993-11-01), None
patent: WO-9322328 (1993-11-01), None
patent: WO-95/11681 (1995-05-01), None
patent: WO-96/02553 (1996-02-01), None
patent: WO-96/04280 (1996-02-01), None
patent: WO-98/47509 (1998-10-01), None
patent: WO-98/57651 (1998-12-01), None
patent: WO-98/57661 (1998-12-01), None
patent: WO-9857651 (1998-12-01), None
patent: WO-99/34804 (1999-07-01), None
patent: WO-99/38877 (1999-08-01), None
patent: WO-99/41267 (1999-08-01), None
patent: WO-99/62518 (1999-12-01), None
patent: WO-99/63938 (1999-12-01), None
patent: WO-99/67263 (1999-12-01), None
patent: WO-99/67264 (1999-12-01), None
patent: WO-99/67265 (1999-12-01), None
patent: WO-99/67266 (1999-12-01), None
patent: WO-00/23457 (2000-04-01), None
patent: WO-00/44763 (2000-08-01), None
patent: WO-0044763 (2000-08-01), None
patent: WO-00/72799 (2000-12-01), None
patent: WO-00/78774 (2000-12-01), None
patent: WO-00/78777 (2000-12-01), None
patent: WO-00/78779 (2000-12-01), None
patent: WO-01/94368 (2001-12-01), None
patent: WO-02/09701 (2002-02-01), None
patent: WO-02/22630 (2002-03-01), None
patent: WO-02/096462 (2002-12-01), None
patent: WO-03/004137 (2003-01-01), None
patent: WO-03/014137 (2003-02-01), None
patent: WO-03/029264 (2003-04-01), None
patent: WO-03/086408 (2003-10-01), None
patent: WO-2005/097140 (2005-10-01), None
patent: WO-2005/107463 (2005-11-01), None
patent: WO-2006/015357 (2006-02-01), None
patent: WO-2006/023272 (2006-03-01), None
patent: WO-2006/028618 (2006-03-01), None
patent: WO-2007/092936 (2007-08-01), None
““STN Database Descriptions””,Chemical Abstracts Catalog, (2006), p. 52.
“U.S. Appl. No. 11/672,868, Non-Final Office Action mailed Apr. 13, 2009”, 37 pgs.
“U.S. Appl. No. 11/673,360, Non-Final Office Action mailed Apr. 22, 2009”, 33 pgs.
“Canadian Application Serial No. 2,460,911, Office Action mailed Jun. 12, 2009”, 7 pgs.
“Japanese Application No. 2003-532511, Office Action Mailed Apr. 28, 2009”, 1 pg.
Adah, S. A, et al., “Synthesis of complex ethynyladenosines using organic triflic enolates in palladium-catalyzed reactions: Potential agonists for the adenosine A2 receptor”,Tetrahedron, 53(20), (May 19, 1997), 6747-6754.
Auchampach, et al., “A3 adenosine receptor agonist IB-MECA reduces myocardial ischemia-reperfusion injury in dogs”,Am J Physiol Heart Circ Physiolvol. 285, (2003), pp. H607-H613.
Ballas, S. K, “Sickle Cell Anaemia: Progress in Pathoge nesis and Treatment”,Drugsvol. 62 No. (8), (2002), p. 1143-1172.
Beers, M. H, et al., “The Merck Manual of Diagnosis and Therapy”,Merck Research Laboratories, (1999), 245-256.
Cargnoni, et al., “Role of A2A Receptors in the Modulation of Myocardial Reperfusion damage”,Journal of Cardiovascular Pharmacologyvol. 33 No. (6), (1999), pp. 883-893.
Cristalli, G., et al., “2-Alkynyl derivatives of adenosine-5′-N-ethyluronamide: selective A2 adenosine receptor agonists with potent inhibitory activity
Figler Robert Alan
Linden Joel M.
Macdonald Timothy L.
Murphree Lauren Jean
Rieger Jayson M.
Berch Mark L
Schwegman Lundberg & Woessner, P.A.
University of Virginia Patent Foundation
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