Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-11-23
2008-10-28
Shameem, Golam M (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S300100, C548S301700, C546S268100, C546S268400, C546S272700, C546S273100, C544S106000, C544S111000, C544S132000, C544S139000, C514S385000, C514S231200, C514S231500, C514S232800
Reexamination Certificate
active
07442716
ABSTRACT:
The invention encompasses novel compounds of Formula Ior pharmaceutically acceptable salts thereof. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and are therefore useful to treat pain and/or inflammation from a variety of diseases or conditions, such as osteoarthritis, rheumatoid arthritis and acute or chronic pain. Methods of treating diseases or conditions mediated by the mPGES-1 enzyme and pharmaceutical compositions are also encompassed.
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Chau Anh
Cote Bernard
Ducharme Yves
Frenette Richard
Friesen Richard
Camara Valerie J.
Merck Frosst Canada Ltd.
Panzer Curtis C.
Shameem Golam M
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