2-Oxo-2,6,7,8,9,10 hexahydro-pyrimido[1,2-a]azepines and antiang

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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544282, C07D48704, A61K 31305

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active

044042051

ABSTRACT:
3 Substituted hexahydro-pyrimido[1, 2 a]azepines and quaternary derivatives, useful as antianginals are prepared. Specifically tested are 3 carboxylates and carbo hydrazides. 3 Cyano Carbamonyl and alkyl compounds are also disclosed.

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patent: 3696197 (1972-10-01), Meszalos et al.
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Burger Med. Chem. 2nd Ed., p. 42, Inter. (1960), N.Y. N.Y.
Burger: Medicinal Chemistry, 3rd Ed., Part II, pp. 1078-1082.
The Pharmacological Basis of Therapeutics: Goodman et al., 5.sup.th Ed. (New York 1975), pp. 326, 327, 339, 341.
Aust. J. Chem., pp. 119-127, 28 (1975).

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