Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-06-07
1997-09-02
Morris, Patricia L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
5483114, 5483117, A61K 31415, C07D40512, C07D40912, C07D23350
Patent
active
056631898
ABSTRACT:
The subject invention relates to compounds having the structure: ##STR1## wherein (a) n is an integer from 1 to about 3;
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Chapleo, C.B., J.C. Doxey, P.L. Myers, M. Myers, C.F.C. Smith & M.R. Stillings, "Effect of 1,4-Dioxanyl Substitution on the Adrenergic Activity of Some Standard .alpha.-Adrenoreceptor Agents", European Journal of Medical Chemistry, vol. 24 (1989), pp. 619-622.
Chapleo, C.B., R.C.M. Butler, D.C. England, P.L. Myers, A.G. Roach, C.F.C. Smith, M.R. Stillings & I.F. Tulloch, "Heteroaromatic Analogues of the .alpha..sub.2 -Adrenoreceptor Partial Agonist Clonidine", Journal of Medical Chemistry, vol. 32 (1989), pp. 1627-1630.
Clare, K.A., M.C. Scrutton & N.T. Thompson, "Effects of .alpha..sub.2 -Adrenoreceptor Agonists and of Related Compounds on Agregation of, and on Adenylate Cyclase Activity in, Human Platelets", British Journal of Pharmacology, vol. 82 (1984), pp. 467-476.
Ares Jeffrey Joseph
Maurer Peter Julian
Seibel William Lee
Walker Daniel P.
Graff Milton B.
Hake Richard A.
McMahon Mary Pat
Morris Patricia L.
The Procter & Gamble & Company
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