Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1976-02-26
1977-03-15
Rotman, Alan L.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
2602955C, 424266, C07D21375
Patent
active
040123979
ABSTRACT:
There are prepared compounds of the formula ##STR1## where R.sub.1 is halogen, R.sub.2 and R.sub.3 are hydrogen, halogen, trifluoromethyl, hydroxy, cyano, lower alkyl or lower alkoxy, R.sub.4 is hydrogen or lower alkyl, and R.sub.5 is hydrogen, lower alkyl, benzoyl, substituted benzoyl, lower carbalkoxy or ##STR2## where A is oxygen, sulfur, imino or lower alkylimino and R.sub.6 is lower alkyl, lower alkyl having 1 to 3 halogen atoms, lower alkenyl, hydroxymethyl, carboxymethyl, carb-lower alkoxy methyl, amino lower alkyl or alkylaminoalkyl having 2 to 13 carbon atoms or where any hydroxy or primary or secondary amino group is substituted by an alkanoyl group of 2 to 8 carbon atoms, carbalkoxy having 1 to 6 carbon atoms, carbophenoxy or carbobenzyloxy or a pharmacologically acceptable salt thereof. The compounds are useful in emotional disturbances, tension, anxiety, increased irritability.
REFERENCES:
patent: 3555035 (1971-01-01), Meisels et al.
patent: 3763178 (1973-10-01), Sulkowski
patent: 3781360 (1973-12-01), Topliss
Offermanns Heribert
von Bebenburg Walter
Deutsche Gold- und Silber-Scheideanstalt vormals Roessler
Rotman Alan L.
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