2-aminopyrimidin-4-one nucleic acid labeling compounds

Details 2-aminopyrimidin-4-one nucleic acid labeling compounds 2-aminopyrimidin-4-one nucleic acid labeling compounds

2002-03-12

2008-12-23

Wilson, James O. (Department: 1624)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C536S023100, C536S025100, C544S320000, C544S321000, C549S430000

Reexamination Certificate

active

07468243

ABSTRACT:
Nucleic acid labeling compounds are disclosed having the formula:These compounds are useful for attaching a detectable label to a nucleic acid.

REFERENCES:
patent: 3352849 (1967-11-01), Shen et al.
patent: 3817837 (1974-06-01), Rubenstein et al.
patent: 3850752 (1974-11-01), Schuurs et al.
patent: 3891623 (1975-06-01), Vorbruggen et al.
patent: 3939350 (1976-02-01), Kronick et al.
patent: 3996345 (1976-12-01), Ullman et al.
patent: 4275149 (1981-06-01), Litman et al.
patent: 4277437 (1981-07-01), Maggio
patent: 4366241 (1982-12-01), Tom et al.
patent: 4594339 (1986-06-01), Lopez et al.
patent: 4981783 (1991-01-01), Augenlicht
patent: 4997928 (1991-03-01), Hobbs, Jr.
patent: 5002867 (1991-03-01), Macevicz
patent: 5143854 (1992-09-01), Pirrung et al.
patent: 5151507 (1992-09-01), Hobbs, Jr. et al.
patent: 5202231 (1993-04-01), Drmanac et al.
patent: 5242796 (1993-09-01), Prober et al.
patent: 5262536 (1993-11-01), Hobbs, Jr.
patent: 5324633 (1994-06-01), Fodor et al.
patent: 5332666 (1994-07-01), Prober et al.
patent: 5422241 (1995-06-01), Goldrick et al.
patent: 5424186 (1995-06-01), Fodor et al.
patent: 5445934 (1995-08-01), Fodor et al.
patent: 5543292 (1996-08-01), Imai et al.
patent: 5571639 (1996-11-01), Hubbel et al.
patent: 5608063 (1997-03-01), Hobbs, Jr. et al.
patent: 5744305 (1998-04-01), Fodor et al.
patent: 6174998 (2001-01-01), Muhlegger et al.
patent: 6211158 (2001-04-01), Seela et al.
patent: 6864059 (2005-03-01), McGall et al.
patent: 19509038 (1996-09-01), None
patent: 0132621 (1985-02-01), None
patent: 0159719 (1985-10-01), None
patent: 0252683 (1988-01-01), None
patent: 0266787 (1988-05-01), None
patent: 0320308 (1989-06-01), None
patent: 0322311 (1989-06-01), None
patent: 0336731 (1989-10-01), None
patent: 0535242 (1993-04-01), None
patent: 0717113 (1996-06-01), None
patent: 0721016 (1996-07-01), None
patent: 2551442 (1985-03-01), None
patent: 61-109797 (1986-05-01), None
patent: WO-89/10977 (1989-11-01), None
patent: WO-90/00626 (1990-01-01), None
patent: WO-90/03370 (1990-04-01), None
patent: WO-90/04652 (1990-05-01), None
patent: WO-90/15070 (1990-12-01), None
patent: WO-92/02258 (1992-02-01), None
patent: WO-95/00530 (1992-05-01), None
patent: WO-92/10092 (1992-06-01), None
patent: WO-92/10588 (1992-06-01), None
patent: WO-93/16094 (1993-08-01), None
patent: WO-93/17126 (1993-09-01), None
patent: WO-95/04594 (1995-02-01), None
patent: WO-95/04833 (1995-02-01), None
patent: WO-95/04834 (1995-02-01), None
patent: WO-95/11995 (1995-05-01), None
patent: WO-95/20681 (1995-08-01), None
patent: WO-95/30774 (1995-11-01), None
patent: WO-95/35505 (1995-12-01), None
patent: WO-96/28460 (1996-09-01), None
patent: WO-97/10365 (1997-03-01), None
patent: WO-97/27317 (1997-07-01), None
patent: WO-97/28176 (1997-08-01), None
patent: WO-97/29212 (1997-08-01), None
patent: WO-97/39120 (1997-10-01), None
patent: WO-98/11104 (1998-03-01), None
patent: WO-00/06771 (2000-02-01), None
Pankiewicz, K. W.; Matsuda, A.; Watanabe, K. A.; Fox, J. J., Tetrahedron, 40(1), 33-8 (English) 1984.
No Author, “Wikipedia, the free encyclopedia” [online]. Wikimedia Foundation Inc. St. Petersburg, FL, Mar. 2, 2005, p. 4, [retrieved on Mar. 2, 2005]. Retreived from the Internet <http:en.wikipedia.org/wiki/Chemistry#Laws>.
Pankiewicz, K.W., et al., “Selective Methylation of the C-Nucleoside, ψ-Isocytidine and its 2′-Deoxy Analog. Synthesis of 1-Methyl, 3-Methyl and 4-O-Methyl Derivatives”,Tetrahedron, vol. 40, No. 1, (1984), pp. 33-38.
Akita, Y..,et al. ,“Cross-Coupling Reaction of Chloropyrazines with Acetylenes”,Chemical&Pharmaceutical Bulletin, 34 (4), (Apr. 1986),pp. 1447-1458.
Aoyagi, M..,et al. ,“Nucleosides and Nucleotides. 115. Synthesis of 3-Alkyl-3-Deazainosines via Palladium-Catalyzed Intramolecular Cyclization: A New Conformational Lock with the Alkyl Group at the 3-Position of the 3-Deazainosine in Anti-Conformation”,Tetrahedron Letters, 34 (1), (1993),pp. 103-106.
Avila, J..L. ,et al. ,“Biological Action of Pyrazolopyrimidine Derivatives Against Trypanosoma Cruzi. Studies In Vitro and In Vivo”,Comp. Biochem. Physiol., 86C (1), (1987),pp. 49-54.
Barringer,et al. ,“Blunt-end and single-strand ligations byEscherichia coliligase: influence on an in vitro amplification scheme”,Gene, 89, (1990),pp. 117-122.
Basnak, I..,et al. ,“Some 6-Aza-5-Substituted-2′-Deoxyuridines Show Potent and Selective Inhibition of Herpes Simplex Virus Type 1 Thymidine Kinase”,Nucleosides&Nucleotides, 17 (1-3), (1998),pp. 187-206.
Beabealashvilli, R..S. ,et al. ,“Nucleoside 5′-triphosphates modified at sugar residues as substrates for calf thymus terminal deoxynucleotidyl transferase and for AMV reverse transcriptase”,Biochimica et Biophysica Acta, 868, (1986),pp. 136-144.
Bergeron,et al. ,“Reagents for the stepwise functionalization of spermine”,J. Org. Chem., 53, (1998),pp. 3108-3111.
Bergstrom, D..E. ,et al. ,“Design and Synthesis of Heterocyclic Carboxamides as Natural Nucleic Acid Base Mimics”,Nucleosides&Nucleotides, 15 (1-3), (1996),pp. 59-68.
Bobek, M..,et al. ,“Nucleic Acids Components and their Analogues. XCVII. Synthesis of 5-Hydroxymethyl-6-Aza-2′- Deoxyuridine and 5-Hydroxymethyl-6-Aza-2′-Deoxycytidine”,Collection Czechoslov. Chem. Commun., 32, (1967),pp. 3581-3586.
Brody, R..S. ,et al. ,“The Purification of Orotidine-5′-phosphate Decarboxylase from Yeast by Affinity Chromatography”,The Journal of Biological Chemistry, 254 (10), (1979),pp. 4238-4244.
Broude, N.E..,et al. ,“Enhanced DNA sequencing by hyridization”,PNAS, 91, (1994),3072-3076.
Canard, B..,et al. ,“Catalytic editing properties of DNA polymerases”,PNAS, 92, (Nov. 1995),pp. 10859-10863.
Cech, D..,et al. ,“New Approaches Toward the Synthesis of Non-Radioactively Labelled Nucleoside Triphosphates as Terminators for DNA Sequencing”,Collect. Czech. Chem. Commun., 61, Special Issue,(1996),pp. S297-S300.
Chee, M..,et al. ,“Accessing Genetic Information with High-Density DNA Arrays”,Science, 274, (Oct. 25, 1996),pp. 610-614.
Chernetskii, V..P. ,et al. ,“Anomalous nucleosides and related compounds. XIV. Derivatives of 6-azacytidine.”,Chemical Abstracts, 74 (21), Abstract No. 112367j,(1971).
Chidgeavadez, Z..G. ,et al. ,“2′, 3′-Dideoxy-3′ aminonucleoside 5′-triphosphates are the terminators of DNA synthesis catalyzed by DNA polymerases”,Nucleic Acids Research, 12 (3), (1984),pp. 1671-1686.
Chu,et al. ,“General Synthesis of 2′, 3′-dideoxynucleosides and 2′, 3′-didehydro-2′, 3′-dideoxynucleosides”,J. Org. Chem., 54, (1989),pp. 2217-2225.
Cottam, Howard.B. ,et al. ,“New Adenosine Kinase Inhibitors with Oral Antiinflammatory Activity: Synthesis and Biological Evaluation”,Journal of Medicinal Chemistry, 36 (22), (Oct. 29, 1993),pp. 3424-3430.
Curriden, M..,“A New Evidence Tool—First Use of Mitochondrial DNA Test in a U.S. criminal trial”,ABA Journal, (Nov. 1996), 1 p.
Danshcer,et al. ,“Autometallographic silver amplification of colloidal gold”,J. Histotech., 16, (1993),pp. 201-207.
Depelley, J..,et al. ,“New Non-Aromatic Triazinic Nucleosides : Synthesis and Antiretroviral Evaluation of Beta-Ribosylamine Nucleoside Analogs”,Nucleosides&Nucleotides, 15 (5), (1996),pp. 995-1008.
Dueholm,et al. ,“2,3-dideoxy-furanoses in convergent synthesis of 2′,3′-dideoxy nucleosides”, Synthesis, (1992),pp. 1-22.
Edo, K..,et al. ,“Studies on Pyrimidine Derivatives. IX. Coupling Reaction of Mono-substituted Acetylenes with Iodopyrimidines”,Chemical&Pharmaceutical Bulletin, 26 (12), (Dec. 1978),pp. 3843-3850.
Eggers, M.,et al. ,“A Microchip for Quantitative Detection of Molecules Utilizing Luminescent and Radioisotope Reporter Groups”,BioTe

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