2-aminopyridine compounds useful as β-secretase...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C546S311000

Reexamination Certificate

active

07932275

ABSTRACT:
The present invention is directed to 2-aminopyridine compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.

REFERENCES:
patent: 5540938 (1996-07-01), Masterson
patent: 6750232 (2004-06-01), Harada et al.
patent: 6951946 (2005-10-01), Kolb
patent: 2004/0006082 (2004-01-01), Harada et al.
patent: WO 03/106405 (2003-12-01), None
patent: WO2004/080376 (2004-09-01), None
patent: WO 2005/005374 (2005-01-01), None
patent: WO 2006/065204 (2006-06-01), None
Hagmann, et al., Bioorg & Med. Chem. Lett., 10 (2000); 1975-1978.

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