Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2008-01-29
2008-01-29
Coleman, Brenda (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S264110, C544S279000
Reexamination Certificate
active
07323472
ABSTRACT:
The present invention is directed to the novel use of a CSBP/p38 inhibitor for the treatment, including prophylaxis of inflammation enhanced cough in a mammal in need thereof.
REFERENCES:
patent: 3843663 (1974-10-01), Williams et sl.
patent: 4560691 (1985-12-01), Lesher et al.
patent: 4897395 (1990-01-01), Duch et al.
patent: 5409930 (1995-04-01), Spada et al.
patent: 5426110 (1995-06-01), Gossett et al.
patent: 5466692 (1995-11-01), Ellingboe
patent: 5547954 (1996-08-01), Henrie, II et al.
patent: 5597776 (1997-01-01), Bratz et al.
patent: 5620981 (1997-04-01), Blankley et al.
patent: 5733913 (1998-03-01), Blankley et al.
patent: 5733914 (1998-03-01), Blankey et al.
patent: 5760220 (1998-06-01), Giguere et al.
patent: 5767097 (1998-06-01), Tam
patent: 5817670 (1998-10-01), Takayama et al.
patent: 5945422 (1999-08-01), Doherty et al.
patent: 6083948 (2000-07-01), Wilde
patent: 6200977 (2001-03-01), Cusing et al.
patent: 6248225 (2001-06-01), Palaika et al.
patent: 6479463 (2002-11-01), Wang et al.
patent: 6492520 (2002-12-01), Chen
patent: 6498163 (2002-12-01), Boschelli et al.
patent: 6528508 (2003-03-01), Salituro et al.
patent: 6528513 (2003-03-01), Cusing et al.
patent: 6800626 (2004-10-01), Salituro et al.
patent: 6809199 (2004-10-01), Doherty et al.
patent: 6838559 (2005-01-01), Vaccaro et al.
patent: 2003/0114671 (2003-06-01), Chen
patent: 2004/0009993 (2004-01-01), Angiolini et al.
patent: 2004/0063658 (2004-04-01), Roberts et al.
patent: 2004/0142945 (2004-07-01), Barbosa et al.
patent: 2004/0224958 (2004-11-01), Booth et al.
patent: 2004/0235847 (2004-11-01), Quan et al.
patent: 2004/0236084 (2004-11-01), Biwersi et al.
patent: 2004/0242604 (2004-12-01), Bhattacharya et al.
patent: 2005/0187217 (2005-08-01), Wilson et al.
patent: 2005/0272728 (2005-12-01), Altenbach et al.
patent: 0 278 686 (1988-05-01), None
patent: 1-261306 (1989-10-01), None
patent: 2000-38350 (2000-02-01), None
patent: 20000038350 (2000-02-01), None
patent: 2003/127542 (2003-05-01), None
patent: 2004-203751 (2004-07-01), None
patent: WO95/15952 (1995-06-01), None
patent: WO95/19774 (1995-07-01), None
patent: WP 95/33750 (1995-12-01), None
patent: WO97/38992 (1997-10-01), None
patent: WO98/05661 (1998-02-01), None
patent: WO98/08846 (1998-03-01), None
patent: WO98/33798 (1998-08-01), None
patent: WO99/41253 (1999-08-01), None
patent: WO 00/23444 (2000-04-01), None
patent: WO 00/43374 (2000-07-01), None
patent: WO 01/19828 (2001-03-01), None
patent: WO 01/42243 (2001-06-01), None
patent: WO 01/55147 (2001-08-01), None
patent: WO 01/70741 (2001-09-01), None
patent: WO 02/058695 (2002-08-01), None
Borrell,et al., “An unequivocal Synthesis of 4-amino-1,5,6,8-tetra-hydropyrido . . . ”, Coll. Czech. Chem. Commun., 1996, 61(6) pp. 901-909.
Hurlbert, et al., “Studies on Condensed Pyrimidine Systems . . . ”, J. Med. Chem., 1968, vol. 11, pp. 703-707.
Baker et al., Analogs of Tetrahydrofolic acid . . . , J. Heterocyclic Chem., 1964, vol. 1, pp. 263-270.
Anderson et al., “Pyridopyrimidines. 6. Nucleophilic Substitutions . . . ”, J. Org. Chem., 1977, vol. 42, pp. 993-996.
Schoffstall et al., “Synthesis of 5,6-Dihydropyrido . . . ”, J. Org. Chem., 1971, 36(16), pp. 2385-2387.
Victory et al., “New Synthesis of pyrido 2, 3 . . . ”, Heterocycles, 1985, 23(5), pp. 1135-1141.
Victory et al., “Cyclisation of Dinitriles by hyrdogen . . . ”, Heterocycles, 1985, 23(8), pp. 1947-1950.
Vicotry et al., “Nueva sintesis de pririo . . . ”, AFINIDAD, Mar. 1989, vol. 46, pp. 107-113.
Klotzer et al., Monatsh Chem., 1965, vol. 96, p. 1567-1572 (w/translation).
Rewcastle et al., “Tyrosine Kinase Inhibitors . . . ”, Journal of Medicinal Chemistry, 1996 39(6), pp. 1823-1835.
Carboni et al.,Gazzetta Chimica Italiana, vol. 97(8) pp. 1262-1273 (1967).
Carboni et al.,Gazzetta Chimica Italiana, vol. 98(10) pp. 1174-1188 (1968).
Ferrarini et al.,Journal of Heterocyclic Chemistry, vol. 21(2) pp. 417-419 (1984).
Ferrarini et al.,Journal of Heterocyclic Chemistry, vol. 34(5) pp. 1501-1510 (1997).
Herlaar, et al.,Molecular Medicine Today, vol. 5 pp. 439-447 (1999).
Khabar, Khalid,Journal of Interferon&Cytokine Research, vol. 25 pp. 1-10 (2005).
Boehm, et al.,Expert Opinion on Therapeutic Patents, vol. 10(1), pp. 25-37 (2000).
Courtney, S. et al.,Bioorganic&Medicinal Chemistry Letters, vol. 14 pp. 3269-3273 (2004).
Foster, et al.,Drug News Perspect., vol. 13(8) pp. 488-497 (2000).
Hanson, G., Expert Opinion on Therapeutic Patents, vol. 7(7) pp. 729-733 (1997).
Henry, et al.,Bioorganic&Medicinal Chemistry Letters, vol. 8 pp. 3335-3340 (1998).
Herlaar, et al., Molecular Medicine Today, vol. 5 pp. 439-447 (1999).
Lee, et al., Immunopharmacology, vol. 47(2-3) pp. 185-201 (2000).
Marin, et al.,Blood, vol. 98(3) pp. 667-673 (2001).
Underwood, et al.,Journal of Pharmacology and Experimental Therapeutics, vol. 293 (1) pp. 281-288 (2000).
Wadsworth, et al., Journal of Pharmacology and Experimental Therapeutics, vol. 291(2) pp. 680-687 (1999).
Victory et al., “New Synthesis of Pyrido[2,3-d]pyrimidines. III. Nucleophilic Substitution on 4-Amino-2-halo and 2-Amino-4-halo-5,6-dihydropyrido[2,3-d]pyrimidin-7(8H)-ones”, J. Heterocycl. Chem, 1988, vol. 25, pp. 245-247.
Nishikawa et al., Structure-Activity Relationships of the Diuretic Activity of Triaza- and Tetraaza-naphthalen Compounds, Chemical Pharm. Bull., 1976, vol. 24(9), pp. 2057-2077.
Adams Jerry L.
Boehm Jeffrey C.
Hall Ralph
Jin Qi
Kasparec Jiri
Coleman Brenda
Dinner Dara L.
Kinzig Charles M.
SmithKline Beecham Corporation
Venetianer Stephen
LandOfFree
2,4,8-trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 2,4,8-trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2,4,8-trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2747411