2,2-alkyldiylbis(thio)bis(imidazoles) useful for inhibition of t

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546256, C07D40114, A61K 31415

Patent

active

047286563

ABSTRACT:
Novel compounds, pharmaceutical compositions and a method of inhibiting the 5-lipoxygenase products in an animal in need thereof which comprises administering an effective, 5-lipoxygenase pathway inhibiting amount of a 2,2'-[1,2-ethanediylbis-(thio)]-bis-1H-imidazole or 2,2'-[(1,3-propan-2-onediylbis-(thio)]bis-1H-imidazole, or a pharmaceutically acceptable salt thereof, to such animal.

REFERENCES:
patent: 4188397 (1980-02-01), Hill
patent: 4339583 (1982-07-01), Cross et al.

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