16.alpha.-methylation process

Details 16.alpha.-methylation process 16.alpha.-methylation process

1986-11-14

1990-05-29

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540 88, 540 89, 514172, 552505, 552595, 552588, 552574, 552602, C07J 100, A61K 3156

Patent

active

049293958

ABSTRACT:
C.sub.16 -unsaturated corticoids are readily transformed to the corresponding 16.alpha.-methyl-17.alpha.-hydroxy corticoids by use of a .DELTA..sup.17 (.sup.20)-20-silyl ether.

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