15 Hydroxylation of 1.alpha.,2.alpha.-methylene steroids

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing a...

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C12P 3312

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043373119

ABSTRACT:
Steroids of the formula ##STR1## wherein R.sub.1 and R.sub.2 are identical or different and each is hydrogen or the residue of an organic or inorganic acid,
and for the esters (R.sub.1 or R.sub.2 is not H) capable of salt formation, the salts thereof, possess valuable pharmacoligical properties, e.g., good antiandrogenic activity with low progestational activity.

REFERENCES:
patent: 2958031 (1960-11-01), Charney et al.
The Merk Index Ninth Edition, p. 363, (1976).

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