13-(1-Oxyl-2,2,6,6-tetramethylpiperylidenyl-4)hydrazone rubomyci

Details 13-(1-Oxyl-2,2,6,6-tetramethylpiperylidenyl-4)hydrazone rubomyci 13-(1-Oxyl-2,2,6,6-tetramethylpiperylidenyl-4)hydrazone rubomyci

1980-10-02

1982-06-01

Hazel, Blondel

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, C07H 1524

Patent

active

043329349

ABSTRACT:
A novel chemical compound is 13-(1-oxo-2,2,6,6-tetramethylpiperylidenyl-4)hydrazone rubomycin hydrochloride, featuring a paramagnetic center and corresponding to the formula ##STR1## The novel compound is formed by reacting rubomycin base with 1-oxo-2,2,6,6-piperidone-4-hydrazone.
The novel compound is capable of inhibiting the growth of malignant tumors and is applicable in medicine; it features reduced toxicity, higher antitumor activity and a wider range of action as compared to known rubomycin derivatives.

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