11-(substituted phenyl)-estra-4,9-diene derivatives

Details 11-(substituted phenyl)-estra-4,9-diene derivatives 11-(substituted phenyl)-estra-4,9-diene derivatives

1997-09-22

2000-01-04

Dees, Jose' G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514182, 540100, A61K 3156, C07J 1700

Patent

active

060110252

ABSTRACT:
The invention relates to a 11-(substituted phenyl)-estra-4,9-diene derivative of formula I ##STR1## wherein A, X, R.sub.1 and R.sub.2 are as defined by the specification. The compounds of the invention have anti-glucocorticoid activity and can be used in treating or preventing glucocorticoid-dependent diseases.

REFERENCES:
patent: 4634695 (1987-01-01), Torelli et al.

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