11-substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines as antip

Details 11-substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines as antip 11-substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines as antip

1985-03-20

1987-07-21

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540547, C07D41304, A61K 3140, A61K 31445

Patent

active

046818790

ABSTRACT:
There are described novel 11-substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines of the general formula ##STR1## where m and n are each independently 0, 1 or 2 and m+n is 1 or 2, X and Y are each independently hydrogen, loweralkyl or halogen, and R is hydrogen, cyano, --C(NH.sub.2)NOH, ##STR2## unsubstituted loweralkyl, or substituted loweralkyl having one to three substituents each of which being independently cyano, hydroxy, cycloalkyl of 3-6 carbon atoms, furyl, thienyl, ##STR3## k being 1, 2 or 3, W being each indepentently hydrogen, halogen, hydroxy, loweralkyl, trifluoromethyl, loweralkoxy, nitro, amino, diloweralkylamino, phenoxy, or benzyloxy, and Z being hydrogen, loweralkyl or halogen, which are useful as antipsychotic and analgesic agents; novel intermediate compounds therefor; and methods of synthesizing the foregoing compounds.

REFERENCES:
patent: 4029672 (1977-06-01), Effland et al.
patent: 4045448 (1977-08-01), Effland
patent: 4053599 (1977-10-01), Effland
patent: 4107074 (1978-08-01), Effland
patent: 4107187 (1979-09-01), Effland
patent: 4169094 (1979-09-01), Effland
patent: 4169095 (1979-09-01), Effland

Affiliated with

Also associated with

Rating

11-substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines as antip does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 11-substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines as antip, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 11-substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines as antip will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-207523