11-Deoxy anthracycline antibiotics, their preparation and use

Details 11-Deoxy anthracycline antibiotics, their preparation and use 11-Deoxy anthracycline antibiotics, their preparation and use

1979-02-05

1981-01-27

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

260365, 536 17A, A61K 3171, C07H 1524

Patent

active

042475457

ABSTRACT:
Anthracycline antibiotics of the formula: ##STR1## wherein R is --CO--CH.sub.2 OH, --CHOH--CH.sub.3, --CO--CH.sub.3 or --CH.sub.2 --CH.sub.3 having antitumor and antibacterial activity are prepared by culturing a new mutant strain of microorganism designated as Micromonospora peucetica sp. nova and which has been deposited with the American Type Culture Collection under number No. 31366 ATCC.

REFERENCES:
patent: 3976667 (1976-08-01), Kelly
patent: 4039736 (1977-08-01), Nettleton, Jr. et al.
patent: 4064340 (1977-12-01), Wiley et al.

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