Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...
Patent
1980-04-02
1982-09-07
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
Conjugated via claimed linking group, bond, chelating agent,...
260365, 260396R, 260429R, 536 64, A61K 3170, C07H 1524
Patent
active
043483887
ABSTRACT:
11-Amino-11-deoxydaunorubicin and analogs represented by the formula: ##STR1## wherein: R is hydrogen, hydroxy or methoxy; R.sub.1 is hydrogen or hydroxy; and the pharmaceutically acceptable salts thereof.
The compounds are useful in ameliorating tumor growth.
REFERENCES:
patent: 3590028 (1971-06-01), Arcamone et al.
patent: 4031211 (1977-06-01), Patelli et al.
patent: 4046878 (1977-09-01), Patelli et al.
Garland Robert B.
Pappo Raphael
Sollman Paul B.
Brown Johnnie R.
Drehkoff W. Dennis
G.D. Searle & Co.
Nelson Albin James
Tockman Albert
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