Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system
Patent
1984-08-15
1989-08-29
Raymond, Richard L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Four or more ring nitrogens in the bicyclo ring system
546201, 548336, 548468, 548486, C07D41304, C07D40104, C07D40304
Patent
active
048618802
ABSTRACT:
Certain substituted 1-phenyl-3-(aminoalkylidene)-2(1H,3H)-indolones are highly potent gabaergic agents, valuable in the treatment of individuals suffering from schizophrenia or reversing the side effects of a previously or concurrently administered neuroleptic agent; or in the treatment of epilepsy. A wider class of substituted 1-phenyl-3-(aminoalkylidene)-2(1H,3H)-indolones, together with 1-phenyl-3-(2-pyrrolidinylidene)-2(1H,3H)-indolones, and homologs thereof, are valuable in the treatment of anxiety.
REFERENCES:
patent: 3043849 (1962-07-01), Szmuszkovicz
patent: 3215699 (1965-02-01), Shavel et al.
patent: 3506683 (1970-04-01), Anthony et al.
patent: 3642803 (1972-02-01), Welstead
patent: 4145422 (1979-03-01), Winn et al.
patent: 4332804 (1982-06-01), Clark
Lattrell et al., CA 89:179858y Indole-3-carbaldehyde oximes 1978, p. 594.
Meyers et al; Review of Medical Pharmacology, Lange Publicat. 4th 1974, p. 149.
Howard, Jr. Harry R.
Sarges Reinhard
Blackwood Robert K.
Lumb J. Trevor
Morris Patricia L.
Pfizer Inc.
Raymond Richard L.
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