1-Hydroxyalkanamine pyrano[3,4-b]indole derivatives

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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424267, 424274, 544142, 546198, 26032628, 26032629, 2603265B, 2603265SA, 42424857, C07D49104, C07D49504, A61K 3140

Patent

active

041795032

ABSTRACT:
Indole derivatives characterized by having a 1,3,4,9-tetrahydropyrano[3,4-b]indole or 1,3,4,9-tetrahydrothiopyrano[3,4-b]indole nucleus with a hydroxyalkanamine or lower alkoxyalkanamine substituent and a lower alkyl group at position 1 are disclosed. The nucleus is optionally further substituted at position 9 and on the aromatic ring. The derivatives are useful diuretic agents, and methods for their preparation and use are also disclosed.

REFERENCES:
patent: 3843681 (1974-10-01), Demerson et al.
patent: 3880853 (1975-04-01), Demerson et al.

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