1-Halopyrazin- and 1-halopyrimidin-4-amino-4-alkylpiperidines

Details 1-Halopyrazin- and 1-halopyrimidin-4-amino-4-alkylpiperidines 1-Halopyrazin- and 1-halopyrimidin-4-amino-4-alkylpiperidines

1995-06-06

1997-01-21

Gupta, Yogendra N.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514255, 514256, 544326, 544331, 544334, 544336, 544405, 544409, A61K 31505, C07D40104, C07D23942

Patent

active

055959946

ABSTRACT:
The present invention relates to novel heteroarylpiperidines of formula (I): ##STR1## in which Hal is a halogen atom, Alk is a C.sub.1-4 alkyl group and one of X, Y and Z is a nitrogen atom while the others are .dbd.CH--, and their salts. These compounds are useful as 5-HT.sub.3 agonists.

REFERENCES:
patent: 4302455 (1981-11-01), Huff et al.
patent: 5001125 (1991-03-01), Stokbroekx et al.

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