1-(Diarylmethyl)-4-piperidinamine and derivatives thereof

Details 1-(Diarylmethyl)-4-piperidinamine and derivatives thereof 1-(Diarylmethyl)-4-piperidinamine and derivatives thereof

1979-09-12

1981-05-12

Jiles, Henry R.

Harness for working animal

542424, 546223, 546197, 546194, C09B 5500, C07D21156

Patent

active

042673186

ABSTRACT:
1-(Diarylmethyl)-4-piperidinamine and derivatives thereof of the formula ##STR1## or a non-toxic pharmocologically acceptable acid addition salt thereof; wherein Ar, Ar.sup.1 and Ar.sup.2 independently are phenyl, phenyl substituted with up to five halogens, alkyl radicals of 1 to 7 carbon atoms or alkoxy radicals of 1 to 7 carbon atoms, 3,4-(methylenedioxy)phenyl or pyridyl optionally substituted with up to four alkyl radicals of 1 to 7 carbon atoms; and R and R.sup.1 are each hydrogen or together form a double bond between the nitrogen and carbon atoms to which they are attached are disclosed. These compounds are useful because of their anti-convulsant and anti-ulcer activity.

REFERENCES:
patent: 3101341 (1963-08-01), Cusic et al.
patent: 3158609 (1964-11-01), Hamilton et al.
patent: 3531487 (1970-09-01), Berger et al.
Acta Pol Pharm, 34 (3), pp. 241-244 (1977).
C. R. Craig, Arch. Int. Pharmacodynither, 165 (2), pp. 328-336, (1977).
Index Chemicus, vol. 68, Issue 738, Abstract 265900 (1978).

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