1-amino-3-phenoxy propane derivatives as modulator agents and th

Details 1-amino-3-phenoxy propane derivatives as modulator agents and th 1-amino-3-phenoxy propane derivatives as modulator agents and th

1995-06-06

1997-04-22

Gupta, Yogendra N.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514317, 514318, 514326, 514336, 544359, 544360, 544369, 544398, 546194, 546209, 5462774, 548203, 548235, 548247, 548452, A61K 31495, A61K 31445, C07D24104, C07D40110

Patent

active

056229534

ABSTRACT:
This invention relates to 1-amino-3-phenoxy-propane-derivatives of formula 1: ##STR1## (in which A, B, R, R.sup.x, X and Z are defined as in the specification described) and methods for their preparation.
These compounds may be used as modulators of multidrug resistance in cancer chemotherapy and for circumvention of resistance in the treatment of malaria.

REFERENCES:
CA 96(25): 217826Y, 1982.
Chem. Pharm. Bull. 31(6), 2023-2032, 1983.

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