1,6-naphthyridine-2(1H)-ones and their use as cardiotonic agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546122, A61K 31435, C07D47104

Patent

active

046579150

ABSTRACT:
5-X-7-R'-1,6-Naphthyridine-2(1H)-ones (formula II) or salts thereof, where X is bromo, chloro or hydrazino and R' is hydrogen or methyl, which are useful as cardiotonic agents.

REFERENCES:
patent: 3993656 (1976-11-01), Rooney et al.
patent: 4038065 (1977-07-01), Johnson et al.
patent: 4415580 (1983-11-01), Lesher et al.
Czuba et al., Pol J. Chem. 52, 2369-76 (1978).
Paudler et al., J. Heterocyclic Chem. 2 (4), 393-8 (1965).

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