1-(6-(2'-substiuted-5', 6', 7', 8'-tetrahydro-4',-oxo-quinazolin

Details 1-(6-(2'-substiuted-5', 6', 7', 8'-tetrahydro-4',-oxo-quinazolin 1-(6-(2'-substiuted-5', 6', 7', 8'-tetrahydro-4',-oxo-quinazolin

1985-04-10

1987-06-30

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514234, 544116, 544284, 544287, 544289, 546147, A61K 31505, C07D40104

Patent

active

046771093

ABSTRACT:
The invention relates to new 1-[6-(2'-substituted-5', 6', 7', 8'-tetrahydro-4'-oxo-quinazolino)]-3,4-dihydro-6,7-disubstituted-isoquinol ine derivatives of the formula (I) ##STR1## wherein R.sup.1 and R.sup.2 each independently represents hdyroxyl or alkoxy having from 1 to 6 carbon atoms,

REFERENCES:
patent: 4522945 (1985-06-01), Vandenberk et al.
Bernath, et al., "Acta. Chim. Acad. Sci. Hung.", vol. 65, 1970, pp. 347-368.
Kerley, et al., "J. Pharm. Exp. Ther." vol. 132, 1961, pp. 360-365.
Brown, Fused Pyrimidines, Part 1, Quinazolines, 1967, Interscience Publishers, N.Y., pp. 116-120, 133-134.

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