1-[4-arylpiperazin-1-yl]-3-[2-oxopyrrolidin/piperidin-1-yl]propa

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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51425309, 51425401, 544360, 544364, 544372, A61K 31496, C07D40106, C07D40114, C07D40306

Patent

active

061503673

ABSTRACT:
A chemical compound and composition of Formula 1: ##STR1## wherein Ar represents a phenyl ring substituted by the groups like halo, alkoxy, alkyl or heteroaryl, n=1 or n=2; said compounds and compositions as being useful therapeutic agents for hypertension, ischemic, cardiovascular and other adrenergic receptor related disorders.

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Medline Abstract for Cooke et al, Vascular Medicine 2 (1), pp. 1-7 (1997), 1998.
Rachman et al, Diabetic Medicine, 12 (6) pp. 467-478, 1995.
Drug Evaluations by the American Medical Association, pp. 575-579, 1993.

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