1,4,10,13-tetraoxa-7,16-diazacyclooctadecane derivatives, pharma

Details 1,4,10,13-tetraoxa-7,16-diazacyclooctadecane derivatives, pharma 1,4,10,13-tetraoxa-7,16-diazacyclooctadecane derivatives, pharma

1993-08-06

1995-08-08

Page, Thurman K.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

540467, 424464, 424443, 424 45, 424489, 424451, 424DIG15, C07D22502, A61K 902

Patent

active

054400317

ABSTRACT:
The invention relates to partially novel metal complexes, salts and double salts of 1,4,10,13-tetraoxa-7,16-diazacyclooctadecane compounds of the formula (I), ##STR1## wherein Q.sup.1 and Q.sup.2 mean hydrogen or a group of the formula (III), ##STR2## in the groups of the formula (III) the R subtituents independently represent hydrogen, a C.sub.1-5 straight or branched chain alkyl group, a C.sub.2-5 straight or branched chain alkenyl group, phenyl or phenyl-C.sub.1-5 alkyl group, the two latter ones optionally being substituted on their aromatic part by one or more halogen(s), C.sub.1-5 alkyl, C.sub.1-5 alkoxy, cyano or nitro group(s), with the proviso that at least one of Q.sup.1 and Q.sup.2 is other than hydrogen;

REFERENCES:
patent: 4597903 (1986-07-01), Gokel et al.
patent: 4687844 (1987-08-01), Gokel et al.
Chemical Abstracts, vol. 111, No. 15, Item No. 134408h.
Chemical Abstracts, vol. 111, No. 14, Item No. 125695x.
Chemical Abstracts, vol. 116, No. 10, Item No. 98085t.
Chemical Abstracts, vol. 115, No. 24, Item No. 269242c.

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