[1,3]-Dioxolo[4,5-f]benzimidazoles and [1,4]-dioxino[2,3-f]benzi

Details [1,3]-Dioxolo[4,5-f]benzimidazoles and [1,4]-dioxino[2,3-f]benzi [1,3]-Dioxolo[4,5-f]benzimidazoles and [1,4]-dioxino[2,3-f]benzi

1984-05-01

1985-12-24

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546271, C07D491056, A61K 31435

Patent

active

045606935

ABSTRACT:
Tricyclic ethers of the general formula I ##STR1## wherein R represents a bond and R1 represents a 1-2C-alkylene radical which is completely or partly substituted by fluorine, or a chlorotrifluoroethylene radical, or R and R1 each represent a difluoromethylene radical, R2 represents hydrogen or a 1-3C-alkyl radical, R3 represents hydrogen or a 1-3C-alkyl or 1-3C-alkoxy radical, R4 represents hydrogen or a 1-3C-alkyl radical and n represents the number 0 or 1, and their salts are new compounds with a marked protective effect on the stomach.

REFERENCES:
patent: 4045563 (1977-08-01), Berntsson et al.
patent: 4045564 (1977-08-01), Berntsson et al.
patent: 4182766 (1980-01-01), Krasso et al.
patent: 4255431 (1981-03-01), Junggren et al.
patent: 4359465 (1982-11-01), Ruwart
patent: 4435406 (1984-03-01), Krasso
patent: 4472409 (1984-09-01), Senn-Bilfinger

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