Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-01-13
2010-06-29
Saeed, Kamal A (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S379400
Reexamination Certificate
active
07745476
ABSTRACT:
The present invention relates to 1,3,5-trisubstituted 4,5-dihydro-1H-pyrazole derivatives as CB1antagonists, to methods for the preparation of these compounds and to novel intermediates useful for the synthesis of said pyrazole derivatives. The invention also relates to the use of a compound disclosed herein for the manufacture of a medicament giving a beneficial effect.The compounds have the general formula (I)wherein the symbols have the meanings given in the specification.
REFERENCES:
patent: 6476060 (2002-11-01), Lange et al.
patent: 2004/0248944 (2004-12-01), Kruse et al.
patent: 2006/0128673 (2006-06-01), Firnges et al.
patent: 2006/0189658 (2006-08-01), Cuberes Altisen et al.
patent: 2007/0015811 (2007-01-01), Cuberes
patent: 2007/0073056 (2007-03-01), Torrens et al.
patent: 3540934 (1987-05-01), None
patent: WO 01/70700 (2001-09-01), None
patent: WO 03/026647 (2003-04-01), None
International Search Report (PCT/EP2005/050339) dated May 6, 2005.
Meschler, J.P. et al. “Inverse Agonist Properties of N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2, dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide HC1(SR141716A) and 1-(2-chlorophenyI)-4-cyano-5-(4-methoxyphenyl)-1H-pyrazole-3-carboxylic acid phenylamide (CP-272871) for CB1 Cannabinoid Receptor,”Biochemical Pharmacology60(2000):1315-1323, Pergamon, Oxford, GB, XP002262541 ISSN: 0006-2952.
Kruse Cornelis G.
Lange Josephus H. M.
Van Stuivenberg Herman H.
Finnegan Henderson Farabow Garrett & Dunner L.L.P.
Saeed Kamal A
Solvay Pharmaceuticals B.V.
LandOfFree
1,3,5-trisubstituted 4,5-dihydro-1H-pyrazole derivatives... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 1,3,5-trisubstituted 4,5-dihydro-1H-pyrazole derivatives..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1,3,5-trisubstituted 4,5-dihydro-1H-pyrazole derivatives... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4232530