1,3,5-Tricarbo-1,4-dihydropyridines

Details 1,3,5-Tricarbo-1,4-dihydropyridines 1,3,5-Tricarbo-1,4-dihydropyridines

1974-02-21

1976-05-11

Jiles, Henry R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424263, 424266, 260295R, 260295AM, 260296D, 260297R, C07D21180

Patent

active

039563413

ABSTRACT:
N-Substituted 1,4-dihydropyridines are prepared by reaction of the corresponding N-unsubstituted 1,4-dihydropyridines with an alkyl haloformate, an acid halide or a carbamyl halide in the presence of base. These compounds have hypotensive activity.

REFERENCES:
patent: 3488359 (1970-01-01), Bossert et al.
patent: 3511847 (1970-05-01), Loev et al.
patent: 3814771 (1974-06-01), Shen et al.
Murakami et al., Chem. Abstracts, Vol. 79, Germ. Offen. 2,302,866, No. 105084 q, Aug. 2, 1973.
Biellmann et al., Chem. Abstracts, Vol. 75, No. 76498 n (1971).

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