1,2-Diphenylpyrrole derivatives, their preparation and their...

Details 1,2-Diphenylpyrrole derivatives, their preparation and their... 1,2-Diphenylpyrrole derivatives, their preparation and their...

2006-12-05

2006-12-05

Stockton, Laura L. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S422000, C548S562000, C548S563000, C548S526000, C548S517000

Reissue Patent

active

RE039420

ABSTRACT:
Compounds of formula (I) and (II):[wherein R is hydrogen, halogen or alkyl; R1is alkyl, amino or substituted amino; R2is optionally substituted phenyl; R3is hydrogen, halogen or optionally substituted alkyl; R4is hydrogen, optionally substituted alkyl, cycloalkyl, aryl, or aralkyl] have valuable analgesic, anti-inflammatory, anti-pyretic and anti-allergic activities and have the ability to inhibit the production of leukotrienes and to inhibit bone resorption. They are relatively free from the side effects which generally result from the administration of compounds having these kinds of activities.

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