1,2-dehydrogenation of steroidal 21-esters with Arthrobacter sim

Details 1,2-dehydrogenation of steroidal 21-esters with Arthrobacter sim 1,2-dehydrogenation of steroidal 21-esters with Arthrobacter sim

1989-09-12

1993-07-06

Robinson, Douglas W.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing a...

435830, 4352521, C12P 3302

Patent

active

052253350

ABSTRACT:
The present invention involves processes for 1,2-dehydrogenation of .DELTA..sup.4 -3-keto C.sub.21 -hemiester steroids of formula (I) ##STR1## with Arthrobacter simplex or Bacterium cyclooxydans to produce the corresponding .DELTA..sup.1,4 -3-keto C.sub.21 hemiester of formula (II) ##STR2## or free alcohol thereof with improved yields. The advantage is that the processes utilize higher substrate concentrations and give shorter reaction times than previously were known.

REFERENCES:
patent: 2822318 (1958-02-01), Kroll
patent: 2837464 (1958-06-01), Nobile
patent: 2902410 (1959-09-01), Weintraub
patent: 2902411 (1959-09-01), Murray
patent: 3360439 (1967-12-01), Erickson
patent: 3770586 (1973-11-01), Kominek
patent: 4524134 (1985-06-01), Kominek
patent: 4704358 (1987-11-01), Kominek

Affiliated with

Also associated with

Rating

1,2-dehydrogenation of steroidal 21-esters with Arthrobacter sim does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1,2-dehydrogenation of steroidal 21-esters with Arthrobacter sim, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1,2-dehydrogenation of steroidal 21-esters with Arthrobacter sim will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1689005