1,2,3,4-Tetrahydroisoquinolines and the preparation thereof

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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546150, C07D21714, A61K 3147

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active

042206472

ABSTRACT:
1,2,3,4-tetrahydroisoquinolines have the formula: ##STR1## wherein R.sub.1 and R.sub.2 are each hydrogen, lower alkyl, lower alkenyl, acyl, aryl or ar(lower)alkyl, in which aryl and the aryl moiety of the ar(lower)alkyl may contain at least one substituent selected from the group consisting of halogen, lower alkoxy, amino, nitro, hydroxy, acyloxy, ar(lower)alkoxy, lower alkylenedioxy, halo(lower)alkyl, acylamino, ar(lower)alkylamino and aryl, and pharmaceutically acceptable salts thereof.

REFERENCES:
patent: 3378561 (1968-04-01), Montzka
patent: 3389140 (1968-06-01), Montzka
patent: 3846432 (1974-11-01), Tanaka et al.

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