1,1′-(1,2-ethynediyl)bis-benzene derivatives as PTP...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

Reexamination Certificate

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C562S422000, C514S595000, C514S576000

Reexamination Certificate



The present invention is related to carboxylic acids of Formula (I) and use thereof for the treatment and/or prevention of obesity and/or metabolic disorders mediated by insulin resistance or hyperglycemia, comprising diabetes type I and/or II, inadequate glucose tolerance, insulin resistance, hyperlipidemia, hypertriglyceridemia, hypercholesterolemia, polycystic ovary syndrome (PCOS). In particular, the present invention is related to the use of carboxylic acids of Formula (I) to modulate, notably to inhibit the activity of PTPs.

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patent: 6479524 (2002-11-01), Priepke et al.
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patent: WO 00/15213 (2000-03-01), None
patent: 00 35859 (2000-06-01), None
patent: 02 04459 (2002-01-01), None
patent: 03 032999 (2003-04-01), None
patent: 03 064376 (2003-08-01), None
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