Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-12-25
2007-12-25
Tucker, Zachary C (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C546S113000, C514S248000, C514S266400, C514S303000, C544S063000, C544S237000, C544S284000
Reexamination Certificate
active
10430024
ABSTRACT:
The present application describes 1,1-disubstituted cycloalkyl compounds and derivatives thereof, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of factor Xa.
REFERENCES:
patent: 3340269 (1967-09-01), Blatter et al.
patent: 3365459 (1968-01-01), Blatter et al.
patent: 3423414 (1969-01-01), Blatter et al.
patent: 5342851 (1994-08-01), Sanfilippo et al.
patent: 5998424 (1999-12-01), Galemmo et al.
patent: 6020357 (2000-02-01), Pinto et al.
patent: 6060491 (2000-05-01), Pruitt et al.
patent: 6191159 (2001-02-01), Pinto et al.
patent: 6271237 (2001-08-01), Galemmo et al.
patent: 6465656 (2002-10-01), Zhou et al.
patent: WO 98/33496 (1998-06-01), None
patent: WO98/28269 (1998-07-01), None
patent: WO98/28282 (1998-07-01), None
patent: WO98/57934 (1998-12-01), None
patent: WO98/57937 (1998-12-01), None
patent: WO98/57951 (1998-12-01), None
patent: WO99/32454 (1999-07-01), None
patent: WO99/32477 (1999-07-01), None
patent: WO99/50255 (1999-10-01), None
patent: WO 00/39108 (2000-07-01), None
patent: WO 00/39131 (2000-07-01), None
patent: WO 00/59902 (2000-10-01), None
patent: WO 01/05784 (2001-01-01), None
patent: WO 01/19798 (2001-03-01), None
patent: WO 01/32628 (2001-05-01), None
patent: WO 02/00655 (2002-01-01), None
Elodi et al., “Optimization of Conditions for the Catalytic Effect of The Factor IXa - Factor VIII Complex: Probable role of the complex in the amplification of blood coagulation”, Thrombosis Research, vol. 15, pp. 617-623, 1979.
Gresele et al., “Novel approaches to the treatment of thrombosis”, TRENDS in Pharmacological Sciences, vol. 23, No. 1, pp. 25-32, Jan. 2002.
Linkins et al., “New Anticoagulants”, Seminars in Thrombosis and Hemostasis, vol. 29, No. 6, pp. 619-631, 2003.
Rauch et al., “Thrombus Formation on Atherosclerotic Plaques: Pathogenesis and Clinical Consequences”, Annals of Internal Medicine, vol. 134, No. 3., pp. 224-238, Feb. 6, 2001.
Ruef et al., “New antithrombotic drugs on the horizon”, Expert Opin. Investig. Drug, vol. 12, No. 5, pp. 781-797, 2003.
Wang et al., “Inhibition of Factor Xa Reduces Ischemic Brain Damage After Thromboembolic Stroke in Rats”, Stroke, pp. 468-474, Feb. 2003.
Wong et al., “Nonpeptide Factor Xa Inhibitors III: Effects of DPC423, an Orally-Active Pyrazole Antithrombotic Agent, on Arterial Thrombosis in Rabbits”, vol. 303, No. 3, pp. 993-1000, 2002.
Friedrich Sarah R.
Han Wei
Orwat Michael J.
Pinto Donald J.
Qiao Jennifer X.
Bristol--Myers Squibb Company
Sun Jing G.
Tucker Zachary C
Vance David H.
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