Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Patent
1990-12-19
1992-02-11
Shen, Cecilia
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
544244, 544277, 544320, A61K 3152, C07D47300, C07D23902
Patent
active
050876970
ABSTRACT:
The present invention relates to 6-substituted purine carbocyclic nucleosides and their use in medical therapy particularly in the treatment of HIV and HBV infections. The invention also relates to pharmaceutical formulations and processes for the preparation of compounds according to the invention.
REFERENCES:
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Davoll, et al., J. Chem. Soc., 1960, pp. 5041-5049, The Synthesis of 9-Glycitylpurines, 3-Glycityl-[1,2,3]-triazolo[d]-pyrimidines, 8-Glycitylpteridines, and 10-Glycitylbenzo[g]pteridines, including Riboflavin and Riboflavin 2-Imine.
Bencini, et al., Analytical Biochemistry, vol. 132, 1983, pp. 254-258, Linear One-Step Assay for the Determination of Orthophosphate.
Sells, et al., Proc. Natl. Acad. Sci. USA, vol. 84, Feb. 1987, pp. 1005-1009, Production of Hepatitis B Virus Particles in Hep G2 Cells Transfected with Cloned Hepatitis B Virus DNA.
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M. Yoshikawa et al., Bulletin Chem. Soc. Japan 1969, 42, 3505.
Brown Donald
Burroughs Wellcome Co.
Green Hannah O.
Nielsen Lawrence A.
Shen Cecilia
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