Chemical apparatus and process disinfecting – deodorizing – preser – Control element responsive to a sensed operating condition
Reexamination Certificate
2004-12-10
2008-08-26
Gordon, Brian R. (Department: 1797)
Chemical apparatus and process disinfecting, deodorizing, preser
Control element responsive to a sensed operating condition
C436S180000, C073S663000, C073S863320, C073S864010, C073S864020, C435S006120
Reexamination Certificate
active
07416705
ABSTRACT:
A spotting device for manufacturing a DNA microarray and a spotting method using the same are provided. The spotting device for dropping and immobilizing a solution of biomolecules, for example nucleic acids such as probe DNA, mRNA, and peptide nucleic acid (PNA), and proteins on a DNA microarray surface to manufacture a DNA microarray, includes a first microchannel with a tube shape; a supplying unit supplying the solution of biomolecules to the first microchannel; a biomolecule solution droplet forming unit cross-linked to the first microchannel and forming biomolecule solution droplets with a predetermined size by periodically jetting a gas toward the biomolecule solution flowing in the first microchannel; a second microchannel linked to the first microchannel and having a greater diameter than the first microchannel; a cooling unit surrounding at least a part of the second microchannel to freeze the biomolecule solution droplets which pass through the second microchannel; and a spotting unit thawing the frozen biomolecule solution droplets and dropping the thawed biomolecule solution droplets on a surface of the DNA microarray. The spotting device can form spots with uniform shape, minimize an effect of temperature on biomolecules, and easily manipulate biomolecules when manufacturing a DNA microarray.
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European Search Report; Application No. EP 04 02 9349; Date: Mar. 31, 2005.
Lee Hun-joo
Lee Jeong-gun
Cantor & Colburn LLP
Gordon Brian R.
Samsung Electronics Co,. Ltd.
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