Cryosurgical technique induction of hyperosmotic condition and w

Surgery – Miscellaneous – Methods

Patent

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606 20, 128DIG27, A61B 1736

Patent

active

059062096

ABSTRACT:
A method for increasing the damage to targeted cells to the point of rupture during freezing while minimizing the freezing of nearby non-targeted tissues comprising: inducing a hyperosmotic condition in the targeted tissue; bloating the targeted tissue; freezing the targeted tissue to cause increase of damage to the targeted tissue to the point of rupture while minimizing freezing of nearby non-targeted tissues.

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patent: 5160313 (1992-11-01), Carpenter et al.
patent: 5658276 (1997-08-01), Griswold
Fahy et al., "Ultrastructure-Function . . . Rat Heart", Cryobiology, vol. 14, pp. 418-427, 1977.
Vinas et al., "Early Hemodynamic . . . Cryogenic Injury", Neurol Res, vol. 17, pp. 465-468, 1995.

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