Pyromellitic diimides and method of increasing feed efficiency i

Details Pyromellitic diimides and method of increasing feed efficiency i Pyromellitic diimides and method of increasing feed efficiency i

1980-04-22

1981-09-15

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Fungus, except allergen, or component thereof or substance...

260326C, A61K 3140, C07D20956

Patent

active

042897840

ABSTRACT:
Novel substituted pyromellitic diimides are disclosed wherein the compounds are assymetrically substituted with a variety of substituent groups. Processes for the preparation of such compounds are also disclosed. The novel assymetrically substituted pyromellitic diimides are useful for administration to ruminant animals to increase feed efficiency, shift volatile fatty acid production in the ruminants from acetate with an increase in the more energetically efficient propionate and butyrate and to suppress methane formation in the rumen. Composition and methods of treatment utilizing said compounds as the active ingredient thereof are also disclosed.

REFERENCES:
patent: 3078228 (1963-02-01), Smith et al.
patent: 3624212 (1971-11-01), Hennart
patent: 3738840 (1973-06-01), Anderson
patent: 3931224 (1976-01-01), Santa et al.
Chem. Abstracts 88:194117d (1978); 84:150376a; 43982y; 13504b (1976); 83:59699b; 82:87103a (1975); 79:19700f (1973); 77:48850u; 76:72279q; 33987x (1972); 75:89332d; 75:63340e; 74:55134m (1971); 71:81122g; 61062j; 70:38694n (1969); 69:97581a; 43899s; 68:59326t; 59329w (1968); 67:116726d (1967); 65:13620f (1966); 63:4435f (1965); 60:4054g (1964); 59:372c (1963).
S. Gitis et al., Zhurnal Organicheskoi Khimii, vol. 2, No. 7, pp. 1265-1267 (1966) Eng. translation, Derivatives of the Diimide of Pyromellitic Acid.

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