PRO1867 polypeptides

Details PRO1867 polypeptides PRO1867 polypeptides

2007-10-23

2007-10-23

Spector, Lorraine (Department: 1646)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C530S387300, C435S069700

Reexamination Certificate

active

10140862

ABSTRACT:
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

REFERENCES:
patent: 5116964 (1992-05-01), Capon et al.
patent: 5536637 (1996-07-01), Jacobs
patent: 6046031 (2000-04-01), Ni et al.
patent: WO 98/31818 (1998-07-01), None
L. Hall, Locus Q9Y3Q7 (encoded by the cDNA of locus HSA133004, GenEmbl, Apr. 10, 1999). Accessed Mar. 3, 2005 (see attached computer printout).
L. Hall, Locus Q95194 (encoded by the cDNA of locus MFTMDCIII, GenEmbl, Oct. 9, 1996). Accessed Mar. 3, 2005 (see attached computer printout).
Hu et al. Analysis of genomic and proteomic data using advanced literature mining. 2003, Journal of Proteome Research 2:405-412.
Saito-Hisaminato et al., Genome-wide profiling of gene expression in 29 normal human tissues with a cDNA microarray. 2002, DNA research, 9:35-45.
S. Vukicevic et al. Induction of nephrogenic mesenchyme by osteogenic protein 1 (bone morphogenetic protein 7). 1996. Proc. Natl. Acad. Sci. USA, 93: 9021-26.
Lilley et al. “Proteomics”. Molecular Biology in Cellular Pathology, (2003) England: John Wiley & Sons, p. 351-352.
Wildsmith et al. “Gene Expression Analysis Using Microarrays”. Molecular Biology in Cellular Pathology, (2003) England: John Wiley & Sons, pp. 269-286.
King, H.C. Gene expression profile analysis by DNA microarrays: promise and pitfalls. 2001, JAMA. 286(18):2280-2288.
Chen et al., Discordant protein and mRNA expression in lung adenocarcinomas. Molecular and Cellular Proteomics, Apr. 2002, vol. 1: 304-313.
Klein et al. Selection for Genes Encoding Secreted Proteins and Receptors.Proc. Natl. Acad. Sci., 93:7108-7113 (1996).
Database Search, DNA Sequence Alignments [BLASTN 2.2.1 [Jul. 12, 2001], NCBI].
Database Search, Protein Sequence Alignments [BLASTP 2.2.1 [Jul. 12, 2002], NCBI].
Frayne et al., “Macaque MDC family of proteins: sequence analysis, tissue distribution and processing in the male reproductive tract”, Mol. Hum. Reprod., vol. 4, No. 5, pp. 429-437, 1998.
Dayhoff, Accession No. P—AAU12229, WO 200140466-A2, Pub Data: Jun. 7, 2001, K. P. Baker et al.
Dayhoff, Accession No. NP—055052.1, Mol. Hum. Reprod. 4 (5), 429-437 (1998), J. Frayne et al.
Dayhoff, Accession No. AD18—HUMAN, Direct Submission, Submitted: Apr. 1999, L. Hall et al.
GenBank, Accession No. P—AAS21301, WO 200140466-A2, Pub Date: Jun. 7, 2001, K. P. Baker et al.
Duchrow, M., et al., “Assessment of Proliferative Activity in Colorectal Carcinomas by Quantitative Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR),”Cancer Invest.—19(6):588-96 (2001) Abstract.
Dyer, J., et al., “Molecular Characterisation of Carbohydrate Digestion Absorption in Equine Small Instestine,”Equine Vet J.—34(4):349-58 (2002) Abstract.
Egwuagu, C.E. et al., “Suppressors of Cytokine Signaling Proteins are Differentially Expressed in Th1 and Th2 Cells: Implications for Th Cell Lineage Commitment and Maintenance,”J. Immunol.—168(7):3181-7 (2002) Abstract.
El-Ghrably, I.A., et al., “Intravitreal Invading Cells Contribute to Vitreal Cytokine Milieu in Proliferative Vitreoretionpathy,”Br J Opthalmol.—85(4):461-70 (2001) Abstract.
Eleore, L., et al., “Modulation of the Glutamatergic Receptors (AMPA and NMDA) and of Glutamate Vesicular Transporter 2 in the Rat Facial Nucleus after Axotomy,”Neuroscience—136(1):147-60 (2005) Abstract.
Forsberg, H., et al., “Altered Levels of Scavenging Enzymes in Embryos Subjected to a Diabotic Environment,”Free Radic Res. —24(6):451-9 (1996) Abstract.
Freyschuss, B., et al., “Induction of the Estrogen Receptor by Growth Hormone and Glucocorticoid Substitution in Priminary Cultures of Rat Hepatocytes,”Endocrinology—133(4):1548-54 (1993) Abstract.
Fu, K., et al., “Cyclin D1-Negative Mantle Cell Lymphoma: A Clinocopathologic Study Based on Gene Expression Profiling,”Blood—106(13):4315-21 (2005) Abstract.
Fuchs, A.R., et al., “Oxytocin Receptors in Bovine Cervix: Distrubution and Gene Expression During the Estrous Cycle,”Biol Reprod.—54(3):700-8 (1996) Abstract.
Furuta, J., et al., “Silencing of the Thrombomodulin Gene in Human Malignant Melanoma,”Melanoma Res.—15(1):15-20 (2005) Abstract.
Futcher, B., et al., “A Sampling of the Yeast Proteome,”Mol Cell Biol.,—19(11):7357-68 (1999) Abstract.
George, J., et al., “Pre-translational Regulation of Cytochrome P450 Genes is Responsible for Disease-Specific Changes of Individual P450 Enzymes Among Patients with Cirrhosis,”Biochem Pharmacol.—49(7):873-81 (1995) Abstract.
Giroux, M., et al., “Cyclooxygenase-2 Expression in Macrophages: Modulation by Protein Kinase C-alpha,”J immunol.—165(7):3985-91 (2000) Abstract.
Gnatenko, D.V., et al., “Transcript Profiling of Human Platelets Using Microarray and Serial Analysis of Gene Expression,”Blood—101(6):2285-93 (2003) Abstract.
Godbout, R., et al., “Overexpression of DEAD Box Protein (DOX1) in Neuroblastoma and Retinoblastoma Cell Lines,”J Biol Chem,—273(33):21161-8 (1998) Abstract.
Goldenberg, R.C., et al., “Modulation of Gap Junction Mediated Intercellular Communication in TM3 Leydig Cells,”J Endocrinol.—177(2):327-35 (2003) Abstract.
Golebiowski, F., et al., “Expression Level of Ubc9 Protein in Rat Tissues,”Acta Biochim Pol.—50(4):1065-73 (2003) Abstract.
Grem, J.L., et al., “Thymidine Kinase, Thymidylate Synthase, and Dihydropyrimidine Dehydrogenase Profiles of Cell Lines of the National Cancer Institute's Anticancer Drug Screen,”Clin Cancer Res. —7(4):999-1009 (2001) Abstract.
Grenback, E., et al., “Galanin Pituitary Adenomas,”Regul Pept,—117(2):127-39 (2004) Abstract.
Gromova, I., et al., “Protein Abundance and mRNA Levels of the Adipocyte-Type Fatty Acid Binding Protein Corrlate in Non-Invasve and Invasive Bladder Transitional Cell Carcinomas,”Int J. Oncol.—13(2):379-83 (1998) Abstract.
Guo, Y., et al., “THe Pathogenic Role of Macrophage Migration Inhibitory Factor in Acute Respiratory Distress Syndrome,” Zhinghua Jie He He Hu Xi Za Zhi—25(6):337-40 (2002) Abstract.
Habu, Y., et al., “Restored Expression and Activity of Organic Ion Transporters rOAT1, rOAT3 and rOCT2 after Hyperuricemia in the Rat Kidney,”Biochem Pharmacol—69(6):993-9 (2005) Abstract.
Hahn, M.E., et al., “Regulation of Cytochrome P4501A1 in Teleosts: Sustained Induction of CYP1A1 mRNA, Protein, and Catalytic Activity by 2,3,7,8-Tetrachlorodibenzofuran in the Marine Fish Stenotomus Chrysops,”Toxicol Appl Pharmacol.—127(2):187-98 (1994) Abstract.
Hahnel, R., et al., “Expression of the pS2 Gene in Breast Tissues Assessed by pS2-mRNA Analysis and pS2-Protein Radioimmunoassay,”Breast Cancer Res Treat.—24(1):71-4 (1992) Abstract.
Hamilton, L.M., et al., “The role of the Epidermal Growth Factor Receptor in Sustaining Neurophil Inflammation in Severe Asthma,”Clin Exp Allergy.—33(2):233-40 (2003) Abstract.
Hassett, C., et al., “Human Hepatic Microsomal Epoxide Hydrolase: Comparative Analysis of Polymorphic Expression,”Arch Biochem Biophys.—337(2):275-83 (1997) Abstract.
Holten-Andersen, M.N., et al., “Localization of Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) in Human Colorectal Adenoma and Adenocarcinoma,”Int J Cance,—113(2):198-206 (2005) Abstract.
Huang, Y.H., e

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