Macrocyclic pyrimidines, their production and use as...

Details Macrocyclic pyrimidines, their production and use as... Macrocyclic pyrimidines, their production and use as...

2007-12-25

2007-12-25

Coleman, Brenda (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S257000, C540S460000, C540S469000, C540S472000

Reexamination Certificate

active

10644076

ABSTRACT:
Macrocyclic pyrimidine derivatives of general formula Iin which R1to R5, X, Y, A, B, m and n have the meanings that are contained in the description, as inhibitors of the cyclin-dependent kinase, their processes for production as well as their use as medications for treating various diseases are described.

REFERENCES:
patent: 4138558 (1979-02-01), Orita et al.
patent: 6235746 (2001-05-01), Davis et al.
patent: WO 0039101 (2000-07-01), None
patent: WO 0164654 (2001-09-01), None
patent: WO 0204429 (2002-01-01), None
patent: WO 0220512 (2002-03-01), None
Knockaert, et al., Pharmacological Inhibitors of Cyclin-Dependent Kinases, TRENDS in Pharmacological Sciences, vol. 23, No. 9, pp. 417-425, Sep. 2002.
Jhaumeer-Laulloo et al., “Synthesis and anti-HIV activity of novel macrocyclic benzamides with a disulfide bridge,” Indian J. Chem., 2000, pp. 842-846, vol. 39B, No. 11, XP009020915, figure 12.
Database Crossfire Beilstein 'Online!, Beilstein Institut zur Foerderung der Chemischen Wissenschaften, XP002261263, Database Accession No. 943696 (BRN), Frankfurt am Main, DE; & Bull. Soc. Sci. Photogr. Jpn., 1969, p. 41, vol. 19.

Affiliated with

Also associated with

Rating

Macrocyclic pyrimidines, their production and use as... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Macrocyclic pyrimidines, their production and use as..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Macrocyclic pyrimidines, their production and use as... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3834129