Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Binds virus or component thereof
Reexamination Certificate
2007-07-17
2007-07-17
Chen, Stacy B. (Department: 1648)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Binds virus or component thereof
C424S137100, C424S218100
Reexamination Certificate
active
11625613
ABSTRACT:
The invention provides human binding molecules specifically binding to West Nile virus and having West Nile virus neutralizing activity, nucleic acid molecules encoding the human binding molecules, compositions comprising the human binding molecules and methods of identifying or producing the human binding molecules. The human binding molecules can be used in the diagnosis, post-exposure prophylaxis and/or treatment of a condition resulting from West Nile virus.
REFERENCES:
patent: 6875433 (2005-04-01), Hart et al.
patent: 6946125 (2005-09-01), Rahal
patent: 7074555 (2006-07-01), Esty et al.
patent: 2003/0148261 (2003-08-01), Fikrig et al.
patent: 2004/0009178 (2004-01-01), Bowdish et al.
patent: 2004/0197769 (2004-10-01), Wong et al.
patent: 2004/0258699 (2004-12-01), Bowdish et al.
patent: 2006/0057149 (2006-03-01), Johnson et al.
patent: 2006/0067940 (2006-03-01), Diamond et al.
patent: 2006/0115837 (2006-06-01), Fremont et al.
patent: 2006/0115896 (2006-06-01), Wong et al.
patent: 2006/0269571 (2006-11-01), Hall et al.
patent: 2007/0025992 (2007-02-01), Takayama et al.
patent: 02/072036 (2002-09-01), None
patent: 2005/007800 (2005-01-01), None
patent: 2005/106483 (2005-11-01), None
patent: 2005/122741 (2005-12-01), None
patent: 2005/123774 (2005-12-01), None
patent: 2006/031825 (2006-03-01), None
patent: 2006/056006 (2006-06-01), None
David W. C. Beasley and Alan D. T. Barrett, Identification of Neutralizing Epitopes within Structural Domain III of the West Nile Virus Envelope Protein, Journal of Virology, Dec. 2002, 76(24):13097-13100.
Goncalvez et al., Chimpanzee Fab Fragments and a Derived Humanized Immunoglobulin G1 Antibody That Efficiently Cross-Neutralize Dengue Type 1 and Type 2 Viruses, Journal of Virology, Dec. 2004, pp. 12910-12918, vol. 78. No. 23.
Chung et al., Antibodies against West Nile Virus Nonstructural Protein NS1 Prevent Lethal Infection through Fc gamma Receptor-Dependent and -Independent Mechanisms, Journal of Virology, Feb. 2006, pp. 1340-1351, vol. 80, No. 3.
Throsby et al., Isolation and Characterization of Human Monoclonal Antibodies from Individuals Infected with West Nile Virus, Journal of Virology, Jul. 2006, pp. 6982-6992, vol. 80, No. 14.
Razumov et al., Neutralizing Monoclonal Antibodies Against Russian Strain of the West Nile Virus, Viral Immunology, 2005, pp. 558-568, vol. 18, No. 3.
Niedrig et al., Monoclonal Antibodies Directed Against Tick-Borne Encephalitis Virus with Neutralizing Activity In Vivo, Acta virologica, 1994, pp. 141-149, vol. 38.
Chen et al., Preparation of monoclonal antibodies against West Nile virus envelope protein domain, Chinese J. Exp. Clin Virol., Sep. 2006, pp. 213-215, vol. 20, No. 3.
Nybakken et al., Structural basis of West Nile virus neutralization by a therapeutic antibody, Nature, Sep. 29, 2005, pp. 764-768, vol. 437.
Blitvich et al., Epitope-Blocking Enzyme-Linked Immunosorbent Assays for the Detection of Serum Antibodies to West Nile Virus in Multiple Avian Species, Journal of Clinical Microbiology, Mar. 2003, pp. 1041-1047, vol. 41, No. 3.
Gould et al., Protective and Therapeutic Capacity of Human Single-Chain Fv-Fc Fusion Proteins against West Nile Virus, Journal of Virology, Dec. 2005, pp. 14606-14613, vol. 79, No. 23.
Roehrig et al., Antibody Prophylaxis and Therapy for Flavivirus Encephalitis Infections, Ann. N. Y. Acad. Sci., Dec. 2001, pp. 286-297, vol. 951.
Oliphant et al., Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus, Nature Medicine, May 2005, pp. 522-530, vol. 11. No. 5.
Sanchez et al., Characterization of neutralizing antibodies to West Nile virus, Virology, 2005, pp. 72-80. vol. 336.
Beasley et al., Identification of Neutralizing Epitopes within Structural Domain III of the West Nile Virus Envelope Protein, Journal of Virology, Dec. 2002, pp. 13097-13100, vol. 76, No. 24.
De Kruif Cornelis Adriaan
Throsby Mark
Chen Stacy B.
Crucell Holland B.V.
TraskBritt
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