Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-11-20
2007-11-20
Pryor, Alton (Department: 1616)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S163000
Reexamination Certificate
active
10871952
ABSTRACT:
The present invention relates to compounds of formula (I)wherein R1, R2, R3R3aand R3bare as provided in the description, and pharmaceutically acceptable salts thereof, for use in the treatment and/or prophylaxis of diseases which are associated with the modulation of CB1 receptors such as obesity.
REFERENCES:
patent: 3940418 (1976-02-01), Hamilton
patent: 5462960 (1995-10-01), Barth et al.
patent: 5596106 (1997-01-01), Cullinan et al.
patent: 5624941 (1997-04-01), Barth et al.
patent: 6433188 (2002-08-01), Corbett et al.
patent: 6441184 (2002-08-01), Corbett et al.
patent: 6448399 (2002-09-01), Corbett et al.
patent: 6545155 (2003-04-01), Corbett et al.
patent: 576357 (1993-06-01), None
patent: 0 604 657 (1994-07-01), None
patent: 656 354 (1994-11-01), None
patent: 656 354 (1994-11-01), None
patent: 658 546 (1994-12-01), None
patent: 658 546 (1994-12-01), None
patent: WO96/02248 (1996-02-01), None
patent: WO97/19063 (1997-05-01), None
patent: WO 00/15609 (2000-03-01), None
patent: WO 00/46209 (2000-08-01), None
patent: WO 01/32663 (2001-05-01), None
patent: WO 01/64632 (2001-09-01), None
patent: WO 01/64633 (2001-09-01), None
patent: WO 01/64634 (2001-09-01), None
patent: WO 01/70700 (2001-09-01), None
patent: WO 02/28346 (2002-04-01), None
patent: WO 03/045386 (2003-06-01), None
Kurzer et al., Heterocyclic compounds from urea derivatives, (J. Chem. Soc., Abs. (1962), 230-6—XP-002296385).
F. Barth, et al., “Cannabinoid antagonists: From research tools to potential new drugs.” Abstracts of Papers, 222ndASC National Meeting, Chicago, IL Aug. 26-30, 2001.
F.M. Casiano, et. al., NIDA Res. Monogr. 105 (1991) 295-6.
G. Colombo, et. al., Life Sci. 63 (8) (1998) L-113-PL117.
W.A. Devane, et. al., Science 258 (1992) 1946-9.
V. Di Marzo, et. al., Nature 410 (6830) 822-825.
V. Di Marzo, et. al, Trends in Neuroscience 21 (12) (1998) 521-8.
C. Felder, et. al., J. Pharmacol. Exp. Ther. 284 (1) (1998) 291-7.
C. Felder, et. al., Proc. Natl. Acad. Sci. USA 90 (16) (1993) 7656-60.
Y. Gaoni, et. al., J. Am. Chem. Soc., 86 (1964) 1646.
K. Hosohata, et. al., Life Sci. 61 (1997) 115-118.
M. Kanyonyo, et. al., Bioorg. Med. Chem. Lett. 9 (15) (1999) 2233-2236.
R. Mechoulam (Ed.) in “Cannabinoids as therapeutic Agents”, (1986) p. 1-20, CRC Press.
S. Munro, et. al., Nature 365 (1993) 61-61.
F. Ooms, et. al., J. Med. Chem 45 (9) (2002) 1748-1756.
M. Pacheco, et. al., J. Pharmacol. Exp. Ther. 257 (1) (1991) 170-183.
R.G. Pertwee, Curr. Med. Chem., 6 (8) (1999) 635-664.
R.G. Pertwee, Life Sci. 56 (23-24) (1995) 1949-55.
R.G. Pertwee, Pharmaceut. Sci. 3 (11) (1997) 539-545.
C. Porter, et. al., Pharmacol. Ther., 90 (1) (2001) 45-60.
D. Shire, J. Biol. Chem. 270 (8) (1995) 3726-31.
C.M. Williams, et. al., Psychopharmacology 143 (3) (1999) 315-317.
E.M. Williamson, et. al., Drugs 60 (6) (2000) 1303-1314.
Kurzer, Frederick et al, Journal of the Chemical Society, Abstracts 230-6 Coden: JCSAAZ; ISSN: 0590-9791 (1962).
Pertwee R.G., Pharmacolog and Therapeutics, XP002226467 vol. 74, No. 2, pp. 129-180 (1997).
Nettekoven Matthias Heinrich
Roever Stephan
Hoffmann-La Roche Inc.
Johnston George W.
Megerditchian Samuel H.
Pryor Alton
Tramaloni Dennis P.
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