Microencapsulation of magnetic material using heat...

Stock material or miscellaneous articles – Coated or structually defined flake – particle – cell – strand,... – Particulate matter

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C264S004700, C264S407000, C264S427000, C264S442000, C428S689000, C428S692100, C424S001210, C424S001370, C424S490000, C424S491000, C424S900000

Reexamination Certificate

active

06989196

ABSTRACT:
Microencapsulation methods and products are provided. The method includes forming, at a first temperature, a emulsion which comprises aqueous microdroplets, including the agent (e.g., a magnetic material or drug) and a cross-linkable matrix material (e.g., a protein such as albumin), dispersed in a hydrophobic continuous phase comprising an oil and an oil-soluble surfactant, the first temperature being below the temperature effective to initiate cross-linking of the matrix material, and then heating the emulsion to a temperature and for a time effective to cause the matrix material to self-crosslink, to form microparticles comprising the agent encapsulated by the crosslinked matrix material.

REFERENCES:
patent: 4774265 (1988-09-01), Ugelstad et al.
patent: 4861627 (1989-08-01), Mathiowitz
patent: 5720921 (1998-02-01), Meserol
patent: 5763203 (1998-06-01), Ugelstad et al.
patent: 5874029 (1999-02-01), Subramaniam et al.
patent: 5985312 (1999-11-01), Jacob et al.
patent: 6048515 (2000-04-01), Kresse et al.
patent: 6129848 (2000-10-01), Chen et al.
patent: 6143211 (2000-11-01), Mathiowitz et al.
patent: 6632671 (2003-10-01), Unger
patent: 6763203 (2004-07-01), Yoshioka et al.
patent: 2003/0086867 (2003-05-01), Lanza et al.
patent: 2003/0146529 (2003-08-01), Chen et al.
Chatterjee, et al., “Modification and characterization of polystyrene-based magnetic microsperes and comparison with albumin-based magnetic microspheres,”J. Magetism&Magnetic Mater. 225:21-29 (2001).
Chatterjee, et al., “Synthesis and characterization of heat-stabilized albumin magnetic microspheres,” Colloid & Polymer Sci., 279:1073-81 (2001).
Gupta, et al., “Albumin microspheres. III. Synthesis and characterization of microspheres containing adriamycin and magnetite,” Int'l J. Pharmaceutics 43:167-77 (1988).
Kyung-Nam Lee, et al., “Synthesis of phenolic/fufural gel microspheres in supercritical CO2,”J. Supercrit. Fluids17:73-80 (2000).
Morimoto & Fujimoto, “Albumin Microspheres as Drug Carriers,”CRC Crit. Rev. Therapeutic Drug Carrier Systems2(1):19-63.
Suslick, et al., “Nanostructured Materials Generated by High-Intensity Ultrasound: Sonochemical Synthesis and Catalytic Studies,”Chem. Mater.8:2172-79 (1996).
Yarovoy, et al., “Submicron-Sized Particles of Ultrahigh Molecular Weight Polyethylene Produced via Nonsolvent and Temperature-Induced Crystallization,”J. Biomed. Mater. Res.(Appl Biomater.) 53:152-60 (2000).
Scheffel, et al., “Albumin Microspheres for Study of the Reticuloendothelial System”J. Nucl. Rad., 13:498-503 (1972).
Zolle, et al., “Preparation of Metabilizable Radioactive Human Serum Albumin Microspheres for Studies of the Circulation”, Int. J. of Applied Radiation and Isotopes 21:155-167 (1970).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Microencapsulation of magnetic material using heat... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Microencapsulation of magnetic material using heat..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Microencapsulation of magnetic material using heat... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3591065

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.