Optically active fluorine-containing compounds and processes...

Details Optically active fluorine-containing compounds and processes... Optically active fluorine-containing compounds and processes...

2005-07-26

2005-07-26

Richter, Johann (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C549S529000, C549S548000, C549S549000, C549S560000, C570S124000

Reexamination Certificate

active

06921832

ABSTRACT:
Optically active fluorine-containing compounds of the formula (1):or of formula (2):are used for producing optically active 3,3,3-trfluoro-2-hydroxy-2-methylpropionic acids.

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Wipf et al. Methyl-and (Trifluoromethyl)alkene Peptide Isosteres: Synethesis and Evaluation of Their Potential as Beta-Turn Promoters and Peptide Mimetics.□□Journal of Organic Chemistry, 1998, vol. 63, p 6088-6089.
Dillon et al, “Asymmetric synthesis of (+)-nemorensic acid-revision of the stereochemistry of the pyrrolizidine alkaloid nemorensine”, Journal of the Chemical Society, Chemical Communications (1995), (16), 1645-6, XP009026929.
Kempf, et al, “Renin Inhibitors Based on Novel Dipeptide Analogues Incorporation of the Dehydrohydroxyethylene Isostere at the Scissile Bond,” Journal of Medicinal Chemistry, vol. 30, No. 11, 1987, pp. 1978-1983, XP002273225.

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