Method for purifying GBS toxin/CM101

Details Method for purifying GBS toxin/CM101 Method for purifying GBS toxin/CM101

1998-02-24

1999-08-17

Witz, Jean C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

435 72, 4352534, 536 6, A01N 4304, C12P 2104, C12N 120, C07J 300

Patent

active

059393963

ABSTRACT:
A method for purifying a polysaccharide from group B .beta.-hemolytic Streptococcus (GBS) bacteria includes contacting a bacterial fermentation stock with a hydrophobic interaction chromatography (HIC) resin. Additional steps may include a phenol/saline extraction and an ion exchange chromatography. The method results in a product having very high purity. The product of the purification provides a composition which is highly useful in both research and therapeutic settings.

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