Antibodies against human IL17 and uses thereof

Details Antibodies against human IL17 and uses thereof Antibodies against human IL17 and uses thereof

2011-08-23

2011-08-23

Jiang, Dong (Department: 1646)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Structurally-modified antibody, immunoglobulin, or fragment...

C530S388230, C530S387300, C530S351000, C530S809000, C435S069100

Reexamination Certificate

active

08003099

ABSTRACT:
An antibody binding to IL-17 characterized by binding to the same IL-17 epitope to which monoclonal antibody 3C1 binds, and being of human IgG1 isotype modified in the hinge region at amino acid position 216-240, preferably at amino acid position 220-240, between CH1 and CH2 and/or in the second inter-domain region at amino acid position 327-331 between CH2 and CH3 has advantageous properties for the treatment of inflammatory diseases.

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