Microfluidic device and method for concentration and lysis...

Details Microfluidic device and method for concentration and lysis... Microfluidic device and method for concentration and lysis...

2011-06-14

2011-06-14

Sakelaris, Sally A (Department: 1773)

Chemical apparatus and process disinfecting, deodorizing, preser

Analyzer, structured indicator, or manipulative laboratory...

Means for analyzing liquid or solid sample

C422S082010, C422S078000, C435S287200, C435S288500, C435S288700, C435S306100, C435S372000, C436S063000, C436S149000

Reexamination Certificate

active

07959862

ABSTRACT:
A microfluidic device for the concentration and lysis of cells or viruses and a method of concentrating and lysing cells or viruses using the microfluidic device include: magnetic beads, a reaction chamber in which the magnetic beads are accommodated and a laser source. The reaction chamber includes a plurality of electrodes which cross each other and are separated by a dielectric to generate an electric field and a vibrating part agitating the magnetic beads in the chamber. The laser source radiates a laser onto the magnetic beads in the reaction chamber.

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Invitrogen manual, Dynabeads Product information.
Mohit D. Dhawan et al.; Development of laser-induced cell lysis system; Anal Bioanal Chem (2002) 374: 421-426.
European Search Report for application No. 06126171.5 dated Apr. 23, 2007.
Microship Laser-Induced Fluorescence Detection of Proteins at Submicrogram per Milliliter Levels Mediated by Dynamic Labeling under Pseudonative Conditions; Braden C. Giordano,†,‡ Lianji Jin,† Abigail J. Couch,† Jerome P. Ferance,† and James P. Landers,†,§; Anal. Chem. 2004, 76, 4705-4714.

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