4-aryl-pyridine-2-carboxyamide derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S342000, C546S256000, C546S270700

Reexamination Certificate

active

07951824

ABSTRACT:
The present invention relates to novel pyridine-2-carboxyamide derivatives of formula (I) useful as metabotropic glutamate receptor antagonists:wherein Y, Z, R1, R2and R3are as defined in the specification herein.

REFERENCES:
patent: 6660753 (2003-12-01), Van Wagenen et al.
patent: 1580056 (2005-02-01), None
patent: 0 321 115 (1989-06-01), None
patent: 1210344 (2002-06-01), None
patent: 2406856 (2005-04-01), None
patent: 2004315395 (2004-11-01), None
patent: WO 98/05651 (1998-02-01), None
patent: WO 02/068417 (2002-09-01), None
patent: WO 03/029210 (2003-04-01), None
patent: WO 03/051315 (2003-06-01), None
patent: WO 03/051833 (2003-06-01), None
patent: WO 03/053922 (2003-07-01), None
patent: WO 03/059904 (2003-07-01), None
patent: WO 2004/058762 (2004-07-01), None
patent: 2005032493 (2005-04-01), None
patent: 2005034870 (2005-04-01), None
patent: WO 2005/044797 (2005-05-01), None
patent: WO 2005/079802 (2005-09-01), None
patent: WO 2006/008545 (2006-01-01), None
patent: WO 2006/016178 (2006-02-01), None
patent: WO 2006/039718 (2006-04-01), None
Nan et al., CAPLUS Abstract 144:468150 (corresponds to CN 1580056 A patent document published Feb. 16, 2005).
Kulkarni et al., Design and synthesis of novel heterobiaryl amides as metabotropic glutamate receptor subtype 5 antagonists, Bioorganic & Medicinal Chemistry Letters, 17(7), pp. 2074-2079, Jan. 4, 2007.
Bonnefous, et al., Bioorganic & Medicinal Chemistry Letters, vol. 15, pp. 1197-1200 (2005).
Mutel, V., Expert Opinion Ther. Patents, vol. 12(12), pp. 1845-1852 (2002).
Schlaeger, et al., Cytotechnology, vol. 30: pp. 71-83 (1999).
Ahn, et al., J. Med. Chem. vol. 40, pp. 2196-2210 (1997).
Felder, E. et al Jour. of Med. Chem., 15(2), pp. 210-211 (1972).
Bonnefous, C. et al, Bioorganic & Medicinal Chem. Letters, 15(4) pp. 1197-1200 (2004).
Lynch, G. S., Expert Opin. Ther. Patents (2002), 12, pp. 11-27.
Guery et al., Synth. Commun. vol. 32 (11), (2002) pp. 1715-1719.
Fife, J. Org. Chem. vol. 48(8) (1983) pp. 1375-1377.
Fife, Heterocycles, vol. 22(1) (1984) pp. 93-95.
Goehring et al., Chimia vol. 50(11) (1996) pp. 538-543.
Schlaeger et al., Cytotechnology, vol. 30, pp. 71-83 (1999).
Porter et al., Br. J. Pharmacol. vol. 128, pp. 13-20 (1999).
Tanga et al., J. Heterocyclic Chem. vol. 34(3), pp. 717-727 (1997).
Kaye, et al., J. C. S. Perkin I, pp. 2335-2339 (1981).
Chemical Abstract XP002430655.
Suzuki et al., Synthesis, (1982) pp. 874-875.
Basha et al., Tetrahedron Lett. (1977) vol. 48, pp. 4171-4174.
Golankiewicz et al., Tetrahedron (1985) vol. 41, pp. 5989-5994.
English Language Abstract Corresponding to CN1580056, 2005.
Chemical Abstract AN:101:72495 Compound, 1984.
English Language Abstract Corresponding to JP2004/315395, 2004.
Nan et al., CAPLUS Abstract 144:468150—CN1580056 Published Feb. 16, 2005.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

4-aryl-pyridine-2-carboxyamide derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 4-aryl-pyridine-2-carboxyamide derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 4-aryl-pyridine-2-carboxyamide derivatives will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2634227

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.