Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1997-12-19
1999-08-31
Campbell, Eggerton A.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 912, C12Q 168, C12P 1934
Patent
active
059452897
ABSTRACT:
Methods for assessing a patient's predisposition for developing prostate cancer are disclosed. PCR assays using primers for apolipoprotein E (ApoE) genotypes and primers for known prostate cancer molecular markers such as PSA are applied to biological samples. ApoE4/E4 homozygosity coupled with elevated PSA or other prostate cancer marker levels in the blood, indicate the likelihood that prostate cancer is present.
REFERENCES:
Gerald P. Murphy, et al., Cancer Aug. 15, 1996, vol. 78 (4): 809-818.
Ya-Ting Chen, et al., Adult Urology, 1996, vol. 47 (4): 518-524.
Albert A. Luderer, Ph.D., et al., Adult Urology, 1995, vol. 46 (2): 187-194.
William J. Catalona, M.D., et al., JAMA, Oct. 18, 1995, vol. 274 (15): 1214-1220.
Gerald Murphy, et al, Anticancer Reserach, 1995, vol. 15: 1473-1480.
Mitchell H. Sokoloff, et al., The Jorunal of Urology, 1996, vol. 156: 1560-1566.
M.H. Sokoloff, et al., The Journal of Urology, 1998, vol. 159: 1.
Graham F. Grene, et al., American Journal of Pathology, May 1997, vol. 150 (5): 1572-1582.
Armelle Degeorges, et al., Int. J. Cancer, 1996, vol. 68: 207-214.
A.M. Saunders, et al., The Lancet, Jul. 13, 1996, vol. 348: 90-93.
Robert W. Mahley, Science, Apr. 29, 1988, vol. 240: 622-630.
Masaaki Miyata, et al., Nature Genetics, Sep. 1996, vol. 14: 55-61.
Susan J. Duthie, et al., Cancer Research, Mar. 15, 1996, vol. 56: 1291-1295.
E. H. Corder, et al., Science, Aug. 13,1993, vol. 261: 921-923.
Peggy Eastman, et al., News, Journal of the National Cancer Inst., Jul. 17, 1996, vol. 88 (14): 952-953.
Joan Stephnenson, Ph.D., JAMA, Sep. 18, 1996, vol. 276 (11): 861-863.
Angelo M. Scanu, The Lancet, May 11, 1991, vol. 337: 1158-1159.
Judes Poirier, et al., The Lancet, Sep. 18, 1993, vol. 342: 697-699.
Daniel Bouthillier, et al, Journal of LIPID Research, 1983, vol. 24: 1060-1069.
D. Blacker, M.D., et al., Neurology, 1997, vol. 48: 139-147.
David A. Twillie, M.D., et al., Urology, Mar. 1995, vol. 45 (3): 542-549.
William J. Catalona, et al., The Journal of Urology, Dec. 1997, vol. 158: 2162-2167.
Steven Lehrer, et al., Journal Cancer Research Clinical Oncology, 1995, vol. 121: 123-125.
Grant E. Meyer, B.S., et al., Cancer, Dec. 1, 1995, vol. 76 (11): 2304-2311 .
LandOfFree
Method for detecting prostate cancer by apolipoprotein E (Apo-E) does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for detecting prostate cancer by apolipoprotein E (Apo-E), we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for detecting prostate cancer by apolipoprotein E (Apo-E) will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2426323