Therapeutic uses of the hypervariable region of monoclonal antib

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,...

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4241331, 4241521, 4241531, 4241551, 4241731, 4241781, 4241831, 5303873, 5303877, 5303882, 5303887, 5303886, 5303888, 5303896, 5303897, 5303913, 5303917, C07K 1628, C07K 1646, A61K 39395

Patent

active

060078146

ABSTRACT:
Therapeutic agents and methods for treating and diagnosing leukemia are provided. Such agents comprises monoclonal antibody M195, a polypeptide capable of binding to the antigen of M195, or a chimeric antibody such a peptide, conjugated to a cytotoxic agent, e.g. a radioisotope or alone. Methods for delivering genetic information to a targeted cell is also provided.

REFERENCES:
patent: 5225539 (1993-07-01), Winter

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